available at:

http://www.delphion.com/

are numerus interesting patents.
they can be viewed in .tiff format (graphic)
and can be downloaded in .pdf format for about $3.00US each.

much of the wording in the patents of tissue culture techniques
didn't give details necessary to reproduce results--
though most of those techniques are available
in scientific journals at the library,
not all seems to be disclosed
and we are left with a mystery.

Searching the patent office does help indicate
what is going on in the (very) private sector.

................................................................

Patent

     US6207455
               Lentiviral vectors

     US6197585
               Human cell-lines

     US6180404
               Cultural medium for maintaining neural cells in ambient atmosphere

     US6162641
               Neuregulin response element and uses therefor

     US6156572
               Bioartificial extracellular matrix containing hydrogel
matrix derivatized with cell adhesive peptide fragment

     US6146888
               Method of enriching for mammalian stem cells

     US6106827
               Method of producing genetically modified astrocytes and uses thereof

     US6103710
               Glucocorticoid response elements

     US6103530
               Cultures of human CNS neural stem cells

     US6087170
               VZV gene, mutant VZV and immunogenic compositions

     US6087167
               Eck receptor ligands

     US6083725
               Tranfected human cells expressing human
.alpha.-galactosidase A protein

     US6066726
               Neuron-specific transcriptional promoter

     US6063630
               Targeted introduction of DNA into primary or secondary cells
and their use for gene therapy

     US6040180
               In vitro generation of differentiated neurons from cultures
of mammalian multipotential CNS stem cells

     US6033906
               Methods for differentiating neural stem cells to glial cells
using neuregulins

     US6020197
               Method for production of neuroblasts

     US6013521
               Method for production of neuroblasts

     US6001654
               Methods for differentiating neural stem cells to neurons or
smooth muscle cells
                using TGT-ß super family growth factors

     US6001557
               Adenovirus and methods of use thereof

     US5994084
               Models of Alzheimer's disease

     US5980885
               Growth factor-induced proliferation of neural precursor
cells in vivo

     US5968829
               Human CNS neural stem cells

     US5958767
               Engraftable human neural stem cells

     US5935856
               Method of inhibiting the growth of BFGF-dependent neoplastic
cells in vitro

     US5916807
               Antisense oligonucleotides against human protein kinase C

     US5908783
               Alternating lysine-alanine copolymer substrate for promoting
neuron survival and
                axon growth

    US5885970
               Antisense oligonucleotides against human protein kinase C

     US5882923
               Glial cell line-derived neurotrophic factor regulation of
ureteric budding and growth

     US5869266
               Human olfactory neuron cultures to diagnose Alzheimer's disease

     US5863797
               Gene fusion encoding a hypersecretor protein

     US5858740
               Method for production of high titer virus and high
efficiency retroviral mediated
               transduction of mammalian cells

     US5858721
               Three-dimensional cell and tissue culture system

     US5851832
               In vitro growth and proliferation of multipotent neural stem
cells and their progeny

     US5849585
               Isolating and culturing Schwann cells

     US5849553
               Mammalian multipotent neural stem cells

     US5837535
               Neuronal-neonatal gene: neuronatin

     US5834029
               Nerve guidance channel containing bioartificial
three-dimensional hydrogel
               extracellular matrix derivatized with cell adhesive
               peptide fragment

    US5830708
               Methods for production of a naturally secreted extracellular matrix

     US5830651
               Human oligodendroglial progenitor cell line

     US5807731
               Glioblastoma cell lines that produce angiogenesis inhibiting factor

     US5795710
               Method and apparatus for organ culture

     US5792900
               Compositions and methods for producing and using homogenous
neuronal cell
               transplants


     US5776743
               Method of sensitizing tumor cells with adenovirus E1A

     US5766948
               Method for production of neuroblasts

     US5753506
               Isolation propagation and directed differentiation of stem
cells from embryonic and
                adult central nervous system of mammals

     US5753491
               Use of neuro-derived fetal cell lines for transplantation therapy

     US5750376
               In vitro growth and proliferation of genetically modified
multipotent neural stem cells
               and their progeny

    US5750103
               Method for transplanting cells into the brain and
therapeutic uses therefor

     US5721139
               Isolating and culturing schwann cells

     US5712160
               Method of stimulating growth using neurotrophic peptides

     US5691201
               Use of sabeluzole in chronic neurodegenerative diseases

     US5681711
               Method for promoting apoptosis in mammalian neual cells

     US5679340
               Cells with multiple altered epitopes on a surface antigen
for use in transplantation

     US5672499
               Immoralized neural crest stem cells and methods of making

     US5672344
               Viral-mediated gene transfer system

     US5654189
               Preparation of pure cultures of post-mitotic human neurons

     US5654188
               Neuroblastoma-associated regulator gene

     US5654183
               Genetically engineered mammalian neural crest stem cells
     US5643773
               Preparation of elongated seamless capsules containing a
coaxial rod and biological
               material

     US5629159
               Immortalization and disimmortalization of cells

     US5627047
               Astrocyte-specific transcription of human genes

     US5595903
               Genetically engineered human acetylcholinesterase

     US5589376
               Mammalian neural crest stem cells

     US5580777
               Generation of neural precursor cell lines

     US5576209
               Method for increasing the resistance of neural cells to
ß-amyloid peptide toxicity

     US5521069
               Genomic DNA exons having exons encoding human pituitary
adenylate cyclase
               activity peptide with 38 amino acids
               residues(PACAP38) and a promoter thereof

     US5436128
               Assay methods and compositions for detecting and evaluating
the intracellular
               transduction of an extracellular signal

     US5429821
               Non-fibrogenic high mannuronate alginate coated transplants,
processes for their
               manufacture, and methods for their use

    US5411883
               Proliferated neuron progenitor cell product and process

     US5362631
               C-myb transfected T98G cells which produce GM-CSF and stem
cell factor

     US5356807
               Cultured cell line of adult diploid cells from human brain
and meningeal tissue

     US5270191
               Method for manipulation of the cell types of eukaryotes

     US5202120
               Methods of reducing glial scar formation and promoting axon
and blood vessel
               growth and/or regeneration through the use
               of activated immature astrocytes

    US5196315
               Human neuronal cell line

     US4707448
               Immortal line of human fetal glial cells

     US4017361
               Process for obtaining continuous lines of tumoral cells in vitro
................................................................


                                 Ray Strand
                             Prairie Sky Design
 -----------------(   on  the Edge of the Prairie Abyss  )---------------
                          when  the  sky  is  clear
                            the ground is visible

                     49/dx PD 2 yrs/40? onset/retired

----------------------------------------------------------------------
To sign-off Parkinsn send a message to: mailto:[log in to unmask]
In the body of the message put: signoff parkinsn