Nilo,
   There are several articles relating SAM-e to parkinson's at
www.ncbi.nlm.nih    Thanks for raising the question.  I bought some today at
Walgreen's and plan to check it out on my own body.  Everything I read about
it is favorable.  Peace
Carl


----- Original Message -----
From: "NILO SARMIENTO" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Thursday, October 04, 2001 7:56 PM
Subject: Has anyone tried SAM-e?


> last week, i saw my neuro, and asked him about SAM-e; he said he had heard
> a lot of good things about it. I asked him if it would be OK for me to
take
> it.  He said, "OK, and let me know what you think of it."
>
> I am currently on sinemet 25/100, 3 times before a meal.  Just lately, a
> fellow staff member who is very much into the Vitamin B family asked me if
> I was taking Vitamin B...I said, No.  I got curious, and did some reading,
> and found that B6 and B12 was good for the nervous system [excerpt
> below]...and I proceeded to click on the link SAM-e.
>
> To make a long story short, when I receive my shipment of SAM-e 400mg
> tomorrow or early next week, I going to include that as part of my
regimen,
> along with the Vitamin B6 and B12.
>
> if any of you has tried this, i'd like to know from your own personal
> experience what the results have been.
>
> What Will B Complex Do For Me?
> You probably didn't know that the most common nutritional deficiency in
the
> world is folic acid deficiency, which is characterized by low mood, and
can
> lead to neural tube defects in the developing, unborn child. Deficiency in
> either vitamins B-12 or B-6 can also bring about low mood, and often mask
> folic acid deficiency (which is why it is so important to take a
supplement
> that is a complete B-complex). In fact, folate supplementation, which in
> large doses requires a doctor's prescription, is a long standing treatment
> in some cases of depression. B vitamins are not stored well in the body
and
> are depleted rapidly in dieters, and caffeine and alcohol users. The
> B-complex is used throughout the body in methylation reactions and is
> particularly effective against low mood, moodiness, muscular weakness and
> fatigue when combined with s-adenosyl methionine (see our SAM-e page for
> more on methylation reactions and SAM-e).
>
>
>
> What Is S-Adenosyl Methionine / SAM-e?
> S-Adenosyl Methionine (SAM or SAM-e; pronounced "sammy") is an amino acid.
> SAM-e was discovered in 1952 in Italy, where it is manufactured. Until
> recently, it was exceedingly expensive to produce, and therefore
> unavailable to the public, although it is fairly well studied. It is
> manufactured in the brain from another amino acid, methionine. SAM-e is
the
> most active methyl-donor in your body, meaning it donates methyl groups to
> other chemical compounds in your body including neurotransmitters,
changing
> them into other compounds. SAM-e is then "recycled" through an ongoing
> re-methylation process - more on this below.
> SAM-e Improves Mood Fast!
> The brain of a healthy person manufactures all the S-Adenosyl Methionine
it
> needs from methionine, but S-Adenosyl Methionine production is impaired in
> people who are depressed.1 Supplementation with SAM-e increases levels of
> serotonin, dopamine and phosphatides, and improves serotonin and dopamine
> receptor site binding.2 Interestingly, treatment with antidepressant drugs
> that results in improved mood (as determined by a 50% improvement in the
> Hamilton Depression Inventory) usually also results in increased levels of
> SAM-e, regardless of the drug used.3
>
> Perhaps the most striking aspect of supplementation with SAM-e, is its
> rapid onset of action. SAM-e has fewer side effects and has a more rapid
> onset of action than tricyclics.1
>
>
> 1 Murray, MT, Natural Alternatives to Prozac. Quill. New York.
p174-5,1996.
> 2 Baldessarini, RJ, Neuropharmacology of S-Adenosyl Methionine. Am J Med.
> 83:95-103, 1983.
>
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