Hi! Ervin:
    I am still taking oral glutathione, along with PS,Vit E, and the rest
might vary depending on my mood.  My pain is down mostly and my tremor is
not as bad as it use to be.  I have lots of energy and a very good appetite,
which was never a trouble for me.
    Recently, I have been having trouble wiht blood pressure (hypertension)
[even before I statrted taking glutathione].  The doctors asked me to take
aspirin every day till they checked me out for a possible heart attack.  All
the tests came out negative.  They told me that even for a PD patient, my
blood pressure was very stable, albeight it is on the upper level.
    When I was getting ready for my blood tests for the above reasons, I
suspended everything and took aspirin only for three days (250 mg of
Bufferin = 1/2 pill of a 500 mg caplet). I had a very pleasant expereince
with aspirin.  All my pains disappeared and I had lots of energy and was
feeling very fresh and active.
    I also read in Dr. Lieberman's column that one of the PWP had a very
similar experience.  But, Dr. Lieberman thought that it is not commonly
reported.  But, it is known that ibuprofen will help PD patients, according
to Dr. Lieberman, since he thinks any anti-inflammatory drug should be of
help for PD patients.  Aspirin also anti-inflammatory! Therefore, after
blood tests were over, I tried both vicia faba beans and ibuprofen and also
80 mg of EC Aspirin for a few days one at a time.  This is the decreasing
order of effective pain relief I experienced with these agents:
    250 mg of Buferin <Vicia faba <ibuprofen 200 mg <80 mg EC aspirin.

    But,  did not want to take bufferin every day (although it is good for
hypertension) due to its adverse effect on the BPH.  So I went back to my
PS, Glutathione routine.
    I thought I shojuld share this with you.
    Raj
[log in to unmask]
******************

----- Original Message -----
From: "Ervin McCarthy" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Sunday, June 09, 2002 9:02 PM
Subject: Re: Raj/glutathione


> Raj, in answer to your question after a two-week layoff of Sinemet I have
> decided today to give Sinemet another try.  I was feeling bad enough and
> desperate enough to try again.  Keep me briefed on apomorphine.  Have you
> heard of any successes on tremors?Best of Luck.
>
> Ervin McCarthy
> ----- Original Message -----
> From: "Brightline" <[log in to unmask]>
> To: <[log in to unmask]>
> Sent: Thursday, June 06, 2002 6:46 PM
> Subject: Re: Raj/glutathione
>
>
> > Ervin:
> >     Thanks for sharing your experience with gluathione injection.
> >     You tell me glutathione did not work for you and so was sinemet.
What
> > are you taking now?
> >     I ran into apomorphine the other day as a substitute for l-dopa and
I
> > posted an article from BMJ a couple of days ago.          However, I am
> told
> > that the effect of apomorphine doesn't last long and it is being used in
> > France to minimise the "off" effect of sinemet.
> >
> > Another chain of thought:
> >     Are these observations trying to tell us something?
> >     1.  I understand that in addition to having se beneficial effect on
PD
> > symptoms, apomorphine is also very effective in erectile disfunction
> > problems and it is coming out as a competitor for viagra with a
different
> > trade name.
> >     2. This brings up some thing else.  If you remember last month or
so,
> > Murray Charters(?) posted a web site for us to watch.   One of the
> articles
> > stated that taking 3-6 mg viagra every day (this is a far lower dose
than
> > 50 - 100 mg / use one takes for erectile disfunction) retarded the
> > progression of PD.  (I have to trace that article and read it again
> > carefully).
> >     3.  A week or so ago, the news release from NIH stated that in about
> 30%
> > (?) of male PD patients, when given testosterone to eliminate
testosterone
> > deficiency, the symptoms of PD faded away. [I am sure testasterone is
made
> > by the female body also; some how female patients were not included in
the
> > test, if I remember right.]
> >      4.  I am taking glutathione orally for the past 10 days or so.  [I
am
> > not yet convinced in the absence of any data that iv injection of
> Glutathine
> > is necesary.]  My energy level is very high and am very active.  I can
> work
> > on the computer for several hours everyday with out suffering any pain
in
> my
> > right shoulder, as I use to.  My stiffness and pain in the calf musle is
> > highly reduced, but not eliminated. Glutathione is an anti-aging
> > antioxident.
> >     I am wondering if all these agents work via similar or related
> > mechanisms.
> >
> >         Raj
> >     [log in to unmask]
> >
> > ----- Original Message -----
> > From: "Ervin McCarthy" <[log in to unmask]>
> > To: <[log in to unmask]>
> > Sent: Thursday, June 06, 2002 8:10 PM
> > Subject: Re: Raj/glutathione
> >
> >
> > > Raj:
> > > Being you mentioned Dr. Perlmutter, I was a patient of his during the
> > winter
> > > months that I spent in Florida.  He seemed to be very knowledgeable
Dr.
> > > three months ago I started on Glutathione here in Michigan.  I took
the
> > > intravenous injections twice a week for six weeks without a positive
> > effect.
> > > I guess I'm one of the unfortunate ones.
> > > It sounds like your taking good care of yourself, by your regimen.
Keep
> > up
> > > the good work.
> > >
> > > Ervin McCarthy
> > > ----- Original Message -----
> > > From: "Brightline" <[log in to unmask]>
> > > To: <[log in to unmask]>
> > > Sent: Tuesday, June 04, 2002 4:33 PM
> > > Subject: Raj/glutathione
> > >
> > >
> > > > Hi! Ervin & Rayilyn:
> > > >     I have never tried Sinemet, eventhough I have a prescrition for
> it.
> > I
> > > > am sure it will be of help, based on the nearly 30 years of
experience
> > > with
> > > > levodopa.  However, I am still reluctant to try it due to its mile
> long
> > > list
> > > > of side effects, (however low freqnuency of occurrence they might
be)
> > and
> > > am
> > > > keeping it handy as a last resort.  I may not be surprised if for
some
> > > > people it does not work.  Even in the NPF info it states that L-dopa
> has
> > > > been shown to be harmful to dopamine producing cells in vitro and in
> > vivio
> > > > in animal studies.  It states that L-dopa may or may not be
> beneficial!
> > > > But, both Dr. AH Rajput and Dr. Jancovics believe, however, it is
not
> > > > harmful to humans.  This is supported by the fact that since the
> > > > introduction of L-dopa or sinemet, people with PD have been living
> > longer.
> > > >     In the article by Dr. Perlmuter, it says that both dopmine and
> > > > glutathione are low in PD patients.  For some reason L-dopa
> application
> > > has
> > > > caught up and the fate of glutatione deficiency has been left
hanging
> in
> > > the
> > > > air.  I have been taking glutathione - reduced for the last week or
> so.
> > I
> > > > definitely feel some improvement in my condition, good enough to
> > postpone
> > > > taking sinement.  I do not know how to quantitate my results. I am
not
> > > sure
> > > > how long this beneficial effect will last.  I would like to know
your
> > > > experience with Glutathione.  One should not expect miracles, since
> > > whatever
> > > > is lost is lost for ever.  I only hope this will slow down the
> > prgression
> > > of
> > > > PD, as evidencd by decrease in and not total elimnation of the
> symptoms
> > of
> > > > PD.
> > > >
> > > >     First thing in the morning I take a cup of greentea with a
> > tablespoon
> > > of
> > > > honey with  no milk or sugar.   Some times I include about 25-50 mg
of
> > > > caffeine pill along with my tea.
> > > >     I am taking glutathione along with phosphatydilserine, B6, B12,
> > > Folate,
> > > > Vitamin E and about 1/3 pill of multivitamain (senior edition with
> less
> > > > amount of iron) every day in the morning just before breakfast.
> > > >     My breakfast consists of bran flakes, about  12 fresh almonds, a
> > pinch
> > > > of peeled pumpkin seeds (for my prostate problems), and a spoon full
> of
> > > > powdered flax seed; this also includes one cup of a fruit juice
> cocktail
> > > > (1:1 mix of orange and tomato juices with a small amount of blue
berry
> > > > juice).
> > > >     (I am a little bit uncertain about the benefit of blue berry or
bb
> > > juice
> > > > for PD patients, since aluminum sulfate is used as a fertlizer for
> blue
> > > > berry plants.  Aluminum has been implicated in PD and in
Alzheimer's.
> > > Does
> > > > anybody know the aluminum content of blue berries? So do I with
regard
> > to
> > > > commercial yogurts.  In 1960s and 70s,  the preservative in
commercial
> > > > yogurt called MSG or monosodium glutamate [also earlier used in
> Chinese
> > > > cooking] has been a contentious issue since in animal studies this
> > caused
> > > > serious nervous system disorders.  Some yogurt products still state
> 1-2%
> > > MG
> > > > on their stickers.  I often wonder is MG is the same as MSG!)  Sorry
> for
> > > > being paranoid.  It is better to be careful, than feeling sorry
later.
> > > >
> > > >     For lunch and supper, I take pretty much anything, except that I
> > make
> > > > sure to take a good dose of fresh vegetables and fruits.
> > > >     Of course, I also include at least 20-30 min of exercise every
> > > morning.
> > > >
> > > >     There is no guarantee that what might seem to work for me may
work
> > for
> > > > everybody, since as you well know, PD is a personalized disease,
often
> > > with
> > > > comomn symptoms that show up at variable rate and similarly, the
> resonse
> > > to
> > > > any drug is also variable between individals.  YOU SHOULD DEFINIELY
> > > CONSULT
> > > > WITH YOR DOCTOR ON ANYTHING YOU TAKE OR DO FOR YOUR PD.
> > > >
> > > > QUESTION:
> > > >     If both dopamine and glutathione are low in PD patients, I would
> ask
> > > > myself if it would make sense to take glutathione in addition to
> > sinemet.
> > > >     BUT, I DON'T HAVE THE ANSWER FOR THIS QUESTION.  SO PLEASE DO
NOT
> > TRY.
> > > > SOME TIMES, THERE COULD BE UNFORSEEN HARMFUL EFFECTS IF TWO DRUGS
ARE
> > > > COMBINED.
> > > >     GOOD EXAMPLE:  A CLINICAL TRIAL WAS STOPPED HALFWAY IN ENGLAND
> > > RECENTLY
> > > > SINCE IT INCREASED MORTALITY RATE AMONG THE GROUP OF PD PATIENTS
THAT
> > WERE
> > > > GIVEN L-DOPA (SINEMET?) AND SELGELINE!
> > > >
> > > >
> > > >     Raj
> > > > [log in to unmask]
> > > > ----- Original Message -----
> > > > From: "Ervin McCarthy" <[log in to unmask]>
> > > > To: <[log in to unmask]>
> > > > Sent: Tuesday, June 04, 2002 9:33 PM
> > > > Subject: Re: Raj/glutathione
> > > >
> > > >
> > > > > Rayilyn, I have gotten the same results from Sinemet on three
> > occasions.
> > > > I
> > > > > was curious if anyone else had the same results.  Now I know.
Thank
> > > you.
> > > > > Ervin McCarthy
> > > > > ----- Original Message -----
> > > > > From: "Rayilyn Brown" <[log in to unmask]>
> > > > > To: <[log in to unmask]>
> > > > > Sent: Monday, June 03, 2002 9:39 PM
> > > > > Subject: Re: Raj/glutathione
> > > > >
> > > > >
> > > > > > Raj,  Thanks for the info on glutathione...that it is a small
> > > molecule.
> > > > > I'm
> > > > > > going to try the oral glutathione first, before intravenous.
> > Sinemet
> > > > > never
> > > > > > helped me much and after a year made dystonia in my feet
> unbearable.
> > > > > I''ve
> > > > > > tried it again 3 times with same result. Rayilyn
> > > > > >
> > > > >
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> > >
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