janet paterson wrote:
>
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> Levodopa pharmacokinetics and dyskinesias: are there sex-related
> differences?
>
> We examined the potential sex-related differences in levodopa
> pharmacokinetics and their relation with the presence of dyskinesias in
> a group of 115 patients (67 men, 49 women) with Parkinson's disease.
>
> The patients were given a standard oral dose of levodopa plus
> benserazide (100/25 mg).
>
> The area under the levodopa plasma concentration time curve, corrected
> for the levodopa test dose (in mg/kg body weight), (AUC(w)) was
> significantly higher in women than in men, with a reduced oral
> clearance.
>
> No difference in the proportion of men and women experiencing
> dyskinesias was observed.
>
> Neurol Sci. 2003 Oct;24(3):192-3.
> Martinelli P, Contin M, Scaglione C, et al.
> Dipartimento di Scienze Neurologiche, Universita di Bologna, Bologna,
> Italy.
> PMID: 14598082
>
> janet paterson
> a new voice http://www.janetpaterson.net/
> pd: 56-41-37 cd: 56-44-43 tel: 613-256-8340
> an akinetic rigid subtype, albeit primarily perky, parky
>
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--
janet paterson
a new voice http://www.janetpaterson.net/
pd: 56-41-37 cd: 56-44-43 tel: 613-256-8340
an akinetic rigid subtype, albeit primarily perky, parky

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