----- Original Message -----
  From: "R.Rajaraman" <[log in to unmask]>
  To: <[log in to unmask]>
  Sent: Tuesday, April 05, 2005 7:59 AM
  Subject: Re: Curcumin inhibits neuronal cell death


  > Both are the same!
  > Raj
  > **********
  > ----- Original Message -----
  > From: "Nick & Oanh" <[log in to unmask]>
  > To: <[log in to unmask]>
  > Sent: Tuesday, April 05, 2005 4:28 AM
  > Subject: Re: Curcumin inhibits neuronal cell death
  >
  >
  >> Raj,
  >>
  >> Thanks for the very detailed reply.
  >> Curious - why do you take Tumeric in stead of  Curcumin?
  >>
  >> Nick
  >>
  >> R.Rajaraman wrote:
  >>
  >> >WARNING:
  >> >        I AM TAKING A CALCULATED RISK IN PRESCIBING MY OWN MEDICATION.
I
  > DO
  >> >THIS AFTER A THOROUGH LITERATURE SURVEY.
  >> >        I AM SHARING MY EXPERIENCE. I AM NOT QUALIFIED TO GIVE ANY
ADVICE
  > TO
  >> >ANYBODY. WHAT WORKS FOR ME MAY NOT WORK FOR EVERYBODY. DO CONSULT A
  >> >QUALIFIED INDIVIDUL BEFORE YOU CHANGE ANYTHING THAT YOU ARE DOING
  > CURRENTLY.
  >> >
  >> >Hi Nick & Oanh:
  >> >    Anybody who knows about the action of sinamet, will opt to stay
out
  > of
  >> >it as long as possible. That was and is my whole aim even today. It is
  >> >unfortunate that no new and useful medication has been invented for
the
  > past
  >> >several decades. I visited my neuro last week. The intern that saw me
for
  >> >almost 40 minutes was trying to push sinemet on me very hard. He
sounded
  >> >worse than the medical sales rep. He insisted that sinemet does not
cause
  >> >dyskenesia!
  >> >    When I told him  that Cox-2 inhibitor is important for slowing the
  >> >progression of PD, he didn't even know about it. That is the kind of
  >> >younger generation of doctors we are training!  After the chief had a
  > talk
  >> >with me, he said more or less the same thing. However, at the end of
my
  >> >visit, another intern came with a questionnaire that she was studying.
  > This
  >> >was about the bad side effects caused by sinamet and the patients
  > aptitude
  >> >with regard to taking sinemet. Both the interns were contradicting
each
  >> >other.
  >> >    To cut the long story short, I still was not convinced enough to
take
  >> >sinemet. I have determined to sty out of it as long as I can manage.
  >> >Therefore, I am still pursuing my multiprong attack and hope I can
solve
  > my
  >> >problems. However, I must say that I have been so far lucky to
  > drastically
  >> >slow down the progression of PD. I cannot still say I have stopped the
  >> >progression completely.
  >> >    Here are the things that I take everyday:
  >> >
  >> >    Morning:
  >> >    20 Min yoga and exercise*
  >> >        Dr. Paneri's medication*
  >> >        Synthroid (for hypothyroidism)
  >> >        Acetyl-l-carnitine**
  >> >        Folic acid for BP & nerves
  >> >        B12
  >> >        Celebrex 100 mg*
  >> >        Brain essentials from Swanson's nutritionals*
  >> >        Co E Q 10 for PD and heart *
  >> >        Green tea capsule
  >> >        MIX of blue berry and pomogranate juice (for Pd and heart)
  >> >        bran cereal + almonds and walnuts
  >> >
  >> >Lunch time:
  >> >        Dr. Paneri's medication
  >> >        Acetyl-l-carnitine
  >> >        Atacand (for Blood Pressure)
  >> >        L-Carnosine**
  >> >        Co E Q10
  >> >        Chondroitin/glucoasmine caps.
  >> >        Multivitamin
  >> >    Omega 3 oil or salmon oil on alternate days or when I don't
consume
  >> >salmon for a few days..
  >> >        Brain essentials*
  >> >        Light lunch with fruits and juices
  >> >
  >> >Supper  time:
  >> >        Dr. Paneri's medication
  >> >        Aceyl-l-carnitine
  >> >        Resveratrol**
  >> >        Brain essentials
  >> >        Turmeric caps  400 mg   (for PD and general health of nerves)
  >> >        Supper with salads, fish or chicken no rice (low carb diet)
  >> >
  >> >before bed time:
  >> >        Atacand for BP.
  >> >    Listen to the Mind Aerobics tape**
  >> >
  >> >*THese items I find very useful.
  >> >** These items have anti-aging, anti-inflammatory, anti-oxidnt,
  >> >neuroprotective and neuro regenerative properties. These should be
  > consumed
  >> >by everybody for general health.
  >> >
  >> >    In general, I avoid beef, rice, and white bread, when ever
possible.
  >> >    I consume plenty of stuff like spinach and stawberries (both great
  > for
  >> >PD). I make it a point to take a variety of fruits, not necessarily
all
  > at
  >> >the same time. The idea is to consume anti-inflammatory,
neuroprotective,
  >> >neuro-regenerative, and antioxidants as much as possible.
  >> >WARNING:
  >> >        I AM TAKING A CALCULATED RISK IN PRESCIBING MY OWN MEDICATION.
I
  > DO
  >> >THIS AFTER A THOROUGH LITERATURE SURVEY.
  >> >        I AM SHARING MY EXPERIENCE. I AM NOT QUALIFIED TO GIVE ANY
ADVICE
  > TO
  >> >ANYBODY. WHAT WORKS FOR ME MAY NOT WORK FOR EVERYBODY. DO CONSULT A
  >> >QUALIFIED INDIVIDUL BEFORE YOU CHANGE ANYTHING THAT YOU ARE DOING
  > CURRENTLY.
  >> > I was diagnosed in 1999. It too me two yearss bfore I understood the
  >> >seriousness of PD and he  woes of allopathic PD medications. I wish I
  >> >started on my protocol much earlier.
  >> >    However, I must say that my friends, including doctors, and my
two
  >> >sons, who are doctors themselves, tell me that I look a lot better
than I
  >> >use to a couple of years ago.  In fact, a medical doctor friend of
mine
  > was
  >> >so impressed with my health improvement, he is prescribing the same
  > things
  >> >to his patient, who did not respond well of the conventional
medicines.
  >> >    I must add that I am painfully aware that I am not out of the
woods
  > yet.
  >> >If everything else fails, I can always starting on sinemet, which
would
  > be
  >> >my last option. I am still on constant look out for alternative
  > medications
  >> >for my PD.
  >> >
  >> >    I hope I have answered your questions.
  >> >    Wishing you all the best.
  >> >    Raj
  >> >********************
  >> >----- Original Message -----
  >> >From: "Nick & Oanh" <[log in to unmask]>
  >> >To: <[log in to unmask]>
  >> >Sent: Saturday, April 02, 2005 6:19 AM
  >> >Subject: Curcumin inhibits neuronal cell death
  >> >
  >> >
  >> >
  >> >
  >> >>Hi Raj,
  >> >>Been following your posts, and the novel way you are combating PD.
  >> >>
  >> >>Would you be so kind and let us know what you are taking now, and how
  >> >>well it's working for you?
  >> >>
  >> >>Thanks in advance,
  >> >>Nick
  >> >>
  >> >>Brightline wrote:
  >> >>
  >> >>
  >> >>
  >> >>>Hi Everybody:
  >> >>>   I was aware that curcumin, an active component of the Indian
spice &
  >> >>>
  >> >>>
  >> >condiment, turmeric, has some protective action against PD and also
has
  >> >certain cancer-killing effect.  The consumption of turmeric is thought
to
  > be
  >> >one of the reasons why PD is rare in Indian population. However, I did
  > not
  >> >know the mechanism of its action. Recently, I ran into some
interesting
  >> >references that claim curcumin inhibits the death of dopaminergic
neurons
  > in
  >> >the MPP+ Parkinson's disease model (Neuropharmacology 2002, 42,
1056-64)
  > by
  >> >inhibiting an enzyme that triggers cell death or apoptosis.  I also
found
  >> >some references to the effect that Omega 3 Fatty Acid (good for the
heart
  >> >too)  also acts in a similar fashion
  >> >
  >> >
  >> >>>   Therefore, I have added these two in my arsenal against the
  >> >>>
  >> >>>
  >> >advacement of PD.  This is for your info only.
  >> >
  >> >
  >> >>>   Please talk to your physician before you change anything.
  >> >>>   Wish you all the best.
  >> >>>   Raj
  >> >>>*********
  >> >>>
  >>
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  >> >>>
  >> >>>
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