There is an interesting discussion of this post on the Huffington post
today.  In light of the recent opening of the "creationist" museum in KY, we
all need to be reminded that the followers of Stone Age theologians endanger
our health by their opposition to science and ESCR.  I always thought that
the theory of evolution answered the "chicken-egg" question.

TB and the Question of Evolution
34 Comments | Posted May 31, 2007 | 10:04 AM (EST)

Read More: Deborah Blum
I recently attended a national meeting of biologists, gathered in dismay
over the way we teach medicine in the United States, at least regarding
basics of biology. At the top of their list was the failure of medical
schools to adequately teach principles of evolution. They blamed such
ignorance for what we all face now -- an unwanted and dangerous experiment
in microbe evolution.
I'm talking, of course, about the rise of antibiotic resistant bacteria. The
"superbugs" are once again in the news following this week's travel fiasco,
involving a Georgia man, who against the advice of his doctors, decided to
fly to Europe for his honeymoon, although he was infected with tuberculosis.
In fact, by the time he arrived in Italy, doctors realized that he was
carrying a worst-case form of the disease called XDR TB, which is highly
infectious, usually fatal, and resistant to almost all available treatment.
The man has since been hustled into quarantine in Atlanta, where the U.S.
Centers for Disease Control is headquartered. The agency has stationed an
armed guard outside his room. CDC is also conducting TB tests on airline
personnel from his Air France flight to Europe and his Czech Air flight back
to North America, in addition to trying to track down and test passengers
seated near the infected passenger.
It would be easy enough to speculate at this point about human stupidity and
its causes. But I don't want to dwell on the passenger in question. I want
to dwell on the mycobacterium responsible for tuberculosis and why it
shape-shifted into a form so potentially deadly that CDC issued its first
quarantine order since 1963. (That order involved a suspected case of
smallpox.)
And that, of course, brings us back to medical schools and the question of
evolution. Today most doctors prescribe antibiotics sparingly but, even 10
years ago, medications were given for
infection the way water is given for thirst. The result was to create a
richly antibiotic-laced world, one that presented bacteria with a
challenging new environment. And microbes responded by adapting, evolving to
meet its pressure. The problem (for us) was not the bacteria that died, but
the ones that contained mutations that allowed them to survive. The
survivors reproduced. Challenged by another drug, they died back except for
a few resistant to both chemical agents. And that scenario repeated itself
to create our current problem. To use TB as an example, there are now more
than half a million people infected with multiple-drug resistant
tuberculosis.
I am somewhat overstating the doctor's responsibility here because the
problem was -- as is -- complicated by patient compliance -- which simply
means that people don't take the drugs as ordered, cut back too soon, allow
the bacteria population to bounce back, newly energized and more resistant.
But it's impossible to overstate the evidence for evolution at work in this
dilemma. If we were half as good as bacteria at evolving to meet challenges,
we'd probably now rule the universe. In fact,
bacteria are such wonderfully adaptive creatures that biologists are now
conducting "experimental evolution" tests with common species such
Escherichia coli -- commonly referred to as e. coli - which thrive in the
human gut. The editor of Physiological and Biochemical Zoology, which plans
to publish those studies this summer, exults that "Now, we can study
evolutionary change as it is happening."
So for all of you who don't believe in the principles of evolution, who
don't get the idea that evolution is, among other things, a foundation of
smart medicine, I suggest you visit Grady Memorial Hospital in Atlanta and
check out the room with the armed guards. Maybe you'll learn something.

----------------------------------------------------------------------
To sign-off Parkinsn send a message to: mailto:[log in to unmask]
In the body of the message put: signoff parkinsn