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There have been questions on deep brain stimulation (DBS), here is
the recent historical and current information on this procedure.
There is a side effect that is common with this procedure which makes it,
rather saving battery life, the reason for turning it off when not
exactly needed to eat, dress or write.
The abstracts follow, the newest study is last, which is from our archives.
ESSENTIAL TREMOR STUDIES & DEVICES
Authors
Lin YC. Lenz FA.
Institution
Department of Neurosurgery, First Hospital, Wenzhou Medical College.
Title
Distribution and response evoked by microstimulation of thalamus nuclei
in patients with dystonia and tremor.
Source
Chinese Medical Journal. 107(4):265-70, 1994 Apr.
Abstract
The effect of 806 microstimulations were observed in 16 patients with
movement disorders, dystonia (DA, n = 6) and tremor (TR, n = 10). Among
the 347 sites in DA patients motor response was seen at 29 sites, the
response with increased dystonia was seen at 28 sites. The effect could
be seen at 14 sites (50%) in ventrointermedialis (Vim), five sites (18%)
in ventrocaudalis (Vc) and five sites (18%) in white matter (Wm). As for
the other four sites, one site was in ventraloralis anterior (Voa), two
sites in ventraloralis posterior (Vop), and one site in dorsal thalamus
(dth), but reduction of dystonia drive was only seen at one site in dth.
On the other hand, among the 459 sites in TR patients, motor response
leading to reduction of tremor drive was seen at 38 sites, of which 30
sites (79%) were noted in Vim nuclei, and five sites (13.2%) in vc
nuclei; of the remaining sites, two were seen in Vop nuclei, one in dth,
and no increasing tremor drive was observed in all area. In general,
paresthesia was the most common response, which was found at 159 sites
(45.8%) with DA and 216 sites (47.1%) with TR. Pain was only seen at
one site in Wm of DA; warm/cold and vertigo could be seen in Vop, Vim,
and vc nucleus respectively. No responses were shown at 156 sites (45%)
in DA, and 201 sites (43.8%) in TR.
Authors
Burleigh AL. Horak FB. Burchiel KJ. Nutt JG.
Institution
Department of Physiology, Oregon Health Sciences University, Portland.
Title
Effects of thalamic stimulation on tremor, balance, and step initiation:
a single subject study.
Source
Movement Disorders. 8(4):519-24, 1993 Oct.
Abstract
This study was conducted to evaluate the clinically apparent balance
improvements in a patient with Parkinson's disease who had stimulating
electrodes surgically implanted to the VIM nucleus of the right thalamus
for control of left-upper-extremity tremor. Experiments were conducted to
determine if balance improved simply because the large-amplitude
upper-extremity tremor was reduced or if the neural control of balance
improved. Using EMGs and forceplate recordings, we quantified the effects
of the thalamic stimulation on the contralateral upper-extremity tremor
and on the lower-extremity postural muscle activations for quiet stance,
step initiation, and equilibrium responses to surface displacements. The
results demonstrated that, beside reducing the amplitude and destabilizing
effects of the upper-extremity tremor, the thalamic stimulation was also
effective in reducing tremor activity of the trunk and contralateral
lower-extremity muscles. In addition, the contralateral lower-extremity
muscle activation patterns, strengths, and durations for the balance tasks
were enhanced during stimulation. These results suggest that thalamic
stimulation improved this patient's balance by reducing tremor in the
contralateral extremities and by increasing burst duration and magnitude
of the tibialis anterior, which functions as the postural prime mover for
the step initiation and balance tasks.
Authors
Nguyen JP. Degos JD.
Institution
Department of Neurosciences, Hopital Henri Mondor, Creteil, France.
Title
Thalamic stimulation and proximal tremor. A specific target in the nucleus
ventrointermedius thalami.
Source
Archives of Neurology. 50(5):498-500, 1993 May.
Abstract
The severe proximal cerebellar postural tremor (also called action or
intention or hyperkinetic tremor) is barely influenced by thalamotomy or
stimulation of the thalamus at the classic target in the lower part of the
nucleus ventrointermedius thalami (VIM). In four patients with a severe
postural distal and proximal tremor, an electrode fitted with four points
of contact was introduced within the entire height of the VIM. In each
patient, stimulation of the lower part of the VIM was most effective in
the distal component of the tremor, whereas its proximal component was
specifically reduced by stimulation of its upper part. These results
indicate that (1) proximal postural tremors can be as much affected by
stimulation of the VIM as distal tremors, (2) there is a somatotopy in the
VIM that is similar to that in the nucleus ventralis posterolateralis
thalami, and (3) it is possible with this technique to adjust the VIM
stimulation site so as to obtain the maximum efficacy according to the
locale of the tremor.
Authors
Benabid AL. Pollak P. Seigneuret E. Hoffmann D. Gay E. Perret J.
Institution
Department of Neurosciences, INSERM 318, France.
Title
Chronic VIM thalamic stimulation in Parkinson's disease, essential tremor
and extra-pyramidal dyskinesias.
Source
Acta Neurochirurgica - Supplementum. 58:39-44, 1993.
Abstract
Stereotactic thalamotomy of the VIM (ventral intermediate) nucleus is
considered as the best neurosurgical treatment for Parkinsonian and
essential tremors. However, this surgery, especially when bilateral, still
presents a risk of recurrence and neurological complications. We observed
that acute VIM stimulation at frequencies higher than 60 Hz during the
mapping phase of the target suppressed the tremor of Parkinson's disease
(PD) and essential tremor (ET). This effect was immediately reversible at
the end of the stimulation. This was initially proposed as an additional
treatment for patients already thalamotomized on the contralateral side,
and then extended as a regular procedure for extra-pyramidal dyskinesias.
Since January 1987, we implanted 126 thalami in 87 patients (61 PD, 13 ET,
13 dyskinesias of various origins). Deep brain stimulation electrodes were
stereotactically implanted under local anaesthesia, using stimulation and
micro-recording to delineate the best site of stimulation. Electrodes were
subsequently connected to implantable programmable stimulators. The
optimal frequency was around 130 to 185 Hz. The results (evaluated by a
neurologist from 0 = no effect to 4 = perfect relief) are related to the
type of tremor. Altogether, 71% of the 80 patients benefited from the
procedure with grade 3 and 4 results. In 88% of the PD cases, the results
were good (grade 3) or excellent (grade 4) and stable with time. Rigidity
was moderately for a long improved but akinesia was not. The same level of
improvement was observed in 68% of the ET patients and only in 18% of the
other types of dyskinesias.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors
Narabayashi H.
Institution
Neurological Clinic, Tokyo, Japan.
Title
Analysis of intention tremor.
Source
Clinical Neurology & Neurosurgery. 94 Suppl:S130-2, 1992.
Abstract
A marked effect of stereotaxic thalamotomy on intention tremor is
described and a neurophysiological interpretation is offered.
Tremor-generating activity seems to start in the ventral intermediate
nucleus (VIM) of the thalamus, as revealed by recording of the unitary
activity through a microelectrode at the tip of the insertion needle,
after diminution of facilitatory input due to pathology of the cerebellum
or its efferent pathway to the cerebrum. This secondary change within the
VIM and the loss of facilitatory input leads to an intention tremor as one
of the cerebellar symptoms seen in various neurological diseases.
Authors
Caparros-Lefebvre D. Blond S. Pecheux N. Pasquier F. Petit H.
Institution
Clinique Neurologique, CHU Lille.
Title
[Neuropsychological evaluation before and after thalamic stimulation in 9
patients with Parkinson disease]. [Review] [French]
Original Title
Evaluation neuropsychologique avant et apres stimulation thalamique chez 9
parkinsoniens.
Source
Revue Neurologique. 148(2):117-22, 1992.
Abstract
Chronic thalamic-VIM stimulation was performed in 9 parkinsonian patients
with disabling tremor and poor response to drugs. Neuropsychological
assessment was performed before and after deep brain electrode
implantation and stimulation. Mild cognitive disorders were observed prior
to thalamic implantation. Neuropsychological testing failed to show
intellectual function worsening after implantation and stimulation. We
conclude that thalamic stimulation could be an appropriate treatment of
untractable tremor as this could provide less neuropsychological
side-effects than thalamotomy, especially in Parkinson's disease.
[References: 43]
Authors
Benabid AL. Pollak P. Gervason C. Hoffmann D. Gao DM. Hommel M.
Perret JE. de Rougemont J.
Institution
Department of Clinical and Biological Neurosciences, INSERM Preclinical
Neurobiology U 318, Joseph Fourier University of Grenoble, France.
Title
Long-term suppression of tremor by chronic stimulation of the ventral
intermediate thalamic nucleus.
Source
Lancet. 337(8738):403-6, 1991 Feb 16.
Abstract
The usefulness of high-frequency stimulation of the ventral intermediate
nucleus (Vim) as the first neurosurgical procedure in disabling tremor was
assessed in 26 patients with Parkinson's disease and 6 with essential
tremor. 7 of these patients had already undergone thalamotomy
contralateral to the stimulated side, and 11 others had bilateral Vim
stimulation at the same time. Chronic stimulating electrodes connected to
a pulse generator were implanted in the Vim. Tremor amplitude at rest,
during posture holding, and during action and intention manoeuvres was
assessed by means of accelerometry. Of the 43 thalami stimulated, 27
showed complete relief from tremor and 11 major improvement (88%). The
improvement was maintained for up to 29 months (mean follow-up 13 [SD 9]
months). Adverse effects were mild and could be eradicated by reduction or
cessation of stimulation. This reversibility and adaptability, allowing
control of side-effects, make thalamic stimulation preferable to
thalamotomy, especially when treatment of both sides of the brain is
needed.
Authors
Pollak P. Benabid AL. Gross C. Gao DM. Laurent A. Benazzouz A.
Hoffmann D. Gentil M. Perret J.
Institution
Departement des Neurosciences Cliniques et Biologiques, Centre
Hospitalier
Universitaire de Grenoble, France.
Title
[Effects of the stimulation of the subthalamic nucleus in Parkinson
disease]. [French]
Original Title
Effets de la stimulation du noyau sous-thalamique dans la maladie de
Parkinson.
Source
Revue Neurologique. 149(3):175-6, 1993.
Abstract
In Parkinson's disease, experimental studies favour a neuronal
hyperactivity of the subthalamic nucleus. We carried out a subthalamic
nucleus electrical stimulation in a patient aged 51, suffering for 8
years from a severe akineto-rigid form of Parkinson's disease,
complicated with an on-off effect. Stereotaxic surgery was done
under local anaesthesia on one side. Within the theoretical target,
a 130 Hz stimulation induced akinesia alleviation mainly on the
contralateral limbs. No abnormal movement was noticed. Then a
long-term quadripolar DBS Medtronic electrode was inserted in that
area. The study of the effects of chronic stimulation is in progress
to determine the best temporal and electrical stimulation
variables.
Treatment of Tremor with Deep-Brain Stimulation
Jean P. Hubble, K. Busenbark, S. Wilkinson, and W.C. Koller,
Kansas City, KS
Objective: To determine the safety, tolerability, and
effectiveness of deep-brain stimulation (DBS) in the treatment
of tremor in essential tremor (ET) and Parkinson's disease (PD).
Background: Tremor in ET and PD is often not satisfactorily
controlled with medication. Thalamotomy can alleviate tremor but
can result in permanent neurological deficits. We hypothesize
that DBS may offer a means of controlling tremor with minimal
attendant risks.
Design/Methods: The DBS lead is stereotactically implanted in
the thalamus (VIM nucleus) contralateral to the arm targeted for
tremor control. The electrical pulse generator is implanted in
the subclavicular region and is turned on/off with a hand-held
external magnet. All subjects have disabling tremor refractory
to conventional pharmacotherapy in the target arm at baseline.
Baseline assessment, DBS placement, and 3-month follow-up
assessment have been completed in 8 ET and 2 PD subjects.
Results: At 3-month follow-up, 8 subjects rated themselves as
markedly (50-100%) improved and 2 as moderately (25-49%)
improved. All subjects had significant tremor reduction in the
target limb with the stimulator "on" compared to "off"
(examiner-rated improvement by >2 points on 0-4 point tremor
rating scale). Nine of the ten subjects had marked improvement
in global disability ratings. All subjects had improved writing
with the stimulator "on". Adverse effects attributable to DBS
included transient paresthesia in all subjects and transient
weakness in 1 subject.
Conclusions: In this 3-month unblinded study, DBS was safe and
effective in reducing tremor and functional disability in ET and
PD.
Study supported by Medtronic Inc. (Neurological Division).
John Cottingham [log in to unmask] OR [log in to unmask]
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August 2003, Week 5 August 2003, Week 4 August 2003, Week 3 August 2003, Week 2 August 2003, Week 1 July 2003, Week 5 July 2003, Week 4 July 2003, Week 3 July 2003, Week 2 July 2003, Week 1 June 2003, Week 5 June 2003, Week 4 June 2003, Week 3 June 2003, Week 2 June 2003, Week 1 May 2003, Week 5 May 2003, Week 4 May 2003, Week 3 May 2003, Week 2 May 2003, Week 1 April 2003, Week 5 April 2003, Week 4 April 2003, Week 3 April 2003, Week 2 April 2003, Week 1 March 2003, Week 5 March 2003, Week 4 March 2003, Week 3 March 2003, Week 2 March 2003, Week 1 February 2003, Week 4 February 2003, Week 3 February 2003, Week 2 February 2003, Week 1 January 2003, Week 5 January 2003, Week 4 January 2003, Week 3 January 2003, Week 2 January 2003, Week 1 December 2002, Week 5 December 2002, Week 4 December 2002, Week 3 December 2002, Week 2 December 2002, Week 1 November 2002, Week 5 November 2002, Week 4 November 2002, Week 3 November 2002, Week 2 November 2002, Week 1 October 2002, Week 5 October 2002, Week 4 October 2002, Week 3 October 2002, Week 2 October 2002, Week 1 September 2002, Week 5 September 2002, Week 4 September 2002, Week 3 September 2002, Week 2 September 2002, Week 1 August 2002, Week 5 August 2002, Week 4 August 2002, Week 3 August 2002, Week 2 August 2002, Week 1 July 2002, Week 5 July 2002, Week 4 July 2002, Week 3 July 2002, Week 2 July 2002, Week 1 June 2002, Week 5 June 2002, Week 4 June 2002, Week 3 June 2002, Week 2 June 2002, Week 1 May 2002, Week 5 May 2002, Week 4 May 2002, Week 3 May 2002, Week 2 May 2002, Week 1 April 2002, Week 5 April 2002, Week 4 April 2002, Week 3 April 2002, Week 2 April 2002, Week 1 March 2002, Week 5 March 2002, Week 4 March 2002, Week 3 March 2002, Week 2 March 2002, Week 1 February 2002, Week 4 February 2002, Week 3 February 2002, Week 2 February 2002, Week 1 January 2002, Week 5 January 2002, Week 4 January 2002, Week 3 January 2002, Week 2 January 2002, Week 1 December 2001, Week 5 December 2001, Week 4 December 2001, Week 3 December 2001, Week 2 December 2001, Week 1 November 2001, Week 5 November 2001, Week 4 November 2001, Week 3 November 2001, Week 2 November 2001, Week 1 October 2001, Week 5 October 2001, Week 4 October 2001, Week 3 October 2001, Week 2 October 2001, Week 1 September 2001, Week 5 September 2001, Week 4 September 2001, Week 3 September 2001, Week 2 September 2001, Week 1 August 2001, Week 5 August 2001, Week 4 August 2001, Week 3 August 2001, Week 2 August 2001, Week 1 July 2001, Week 5 July 2001, Week 4 July 2001, Week 3 July 2001, Week 2 July 2001, Week 1 June 2001, Week 5 June 2001, Week 4 June 2001, Week 3 June 2001, Week 2 June 2001, Week 1 May 2001, Week 5 May 2001, Week 4 May 2001, Week 3 May 2001, Week 2 May 2001, Week 1 April 2001, Week 5 April 2001, Week 4 April 2001, Week 3 April 2001, Week 2 April 2001, Week 1 March 2001, Week 5 March 2001, Week 4 March 2001, Week 3 March 2001, Week 2 March 2001, Week 1 February 2001, Week 4 February 2001, Week 3 February 2001, Week 2 February 2001, Week 1 January 2001, Week 5 January 2001, Week 4 January 2001, Week 3 January 2001, Week 2 January 2001, Week 1 December 2000, Week 5 December 2000, Week 4 December 2000, Week 3 December 2000, Week 2 December 2000, Week 1 November 2000, Week 5 November 2000, Week 4 November 2000, Week 3 November 2000, Week 2 November 2000, Week 1 October 2000, Week 5 October 2000, Week 4 October 2000, Week 3 October 2000, Week 2 October 2000, Week 1 September 2000, Week 5 September 2000, Week 4 September 2000, Week 3 September 2000, Week 2 September 2000, Week 1 August 2000, Week 5 August 2000, Week 4 August 2000, Week 3 August 2000, Week 2 August 2000, Week 1 July 2000, Week 5 July 2000, Week 4 July 2000, Week 3 July 2000, Week 2 July 2000, Week 1 June 2000, Week 5 June 2000, Week 4 June 2000, Week 3 June 2000, Week 2 June 2000, Week 1 May 2000, Week 5 May 2000, Week 4 May 2000, Week 3 May 2000, Week 2 May 2000, Week 1 April 2000, Week 5 April 2000, Week 4 April 2000, Week 3 April 2000, Week 2 April 2000, Week 1 March 2000, Week 5 March 2000, Week 4 March 2000, Week 3 March 2000, Week 2 March 2000, Week 1 February 2000, Week 5 February 2000, Week 4 February 2000, Week 3 February 2000, Week 2 February 2000, Week 1 January 2000, Week 5 January 2000, Week 4 January 2000, Week 3 January 2000, Week 2 January 2000, Week 1 December 1999, Week 5 December 1999, Week 4 December 1999, Week 3 December 1999, Week 2 December 1999, Week 1 November 1999, Week 5 November 1999, Week 4 November 1999, Week 3 November 1999, Week 2 November 1999, Week 1 October 1999, Week 5 October 1999, Week 4 October 1999, Week 3 October 1999, Week 2 October 1999, Week 1 September 1999, Week 5 September 1999, Week 4 September 1999, Week 3 September 1999, Week 2 September 1999, Week 1 August 1999, Week 5 August 1999, Week 4 August 1999, Week 3 August 1999, Week 2 August 1999, Week 1 July 1999, Week 5 July 1999, Week 4 July 1999, Week 3 July 1999, Week 2 July 1999, Week 1 June 1999, Week 5 June 1999, Week 4 June 1999, Week 3 June 1999, Week 2 June 1999, Week 1 May 1999, Week 5 May 1999, Week 4 May 1999, Week 3 May 1999, Week 2 May 1999, Week 1 April 1999, Week 5 April 1999, Week 4 April 1999, Week 3 April 1999, Week 2 April 1999, Week 1 March 1999, Week 5 March 1999, Week 4 March 1999, Week 3 March 1999, Week 2 March 1999, Week 1 February 1999, Week 4 February 1999, Week 3 February 1999, Week 2 February 1999, Week 1 January 1999, Week 5 January 1999, Week 4 January 1999, Week 3 January 1999, Week 2 January 1999, Week 1 December 1998, Week 5 December 1998, Week 4 December 1998, Week 3 December 1998, Week 2 December 1998, Week 1 November 1998, Week 5 November 1998, Week 4 November 1998, Week 3 November 1998, Week 2 November 1998, Week 1 October 1998, Week 5 October 1998, Week 4 October 1998, Week 3 October 1998, Week 2 October 1998, Week 1 September 1998, Week 5 September 1998, Week 4 September 1998, Week 3 September 1998, Week 2 September 1998, Week 1 August 1998, Week 5 August 1998, Week 4 August 1998, Week 3 August 1998, Week 2 August 1998, Week 1 July 1998, Week 5 July 1998, Week 4 July 1998, Week 3 July 1998, Week 2 July 1998, Week 1 June 1998, Week 5 June 1998, Week 4 June 1998, Week 3 June 1998, Week 2 June 1998, Week 1 May 1998, Week 5 May 1998, Week 4 May 1998, Week 3 May 1998, Week 2 May 1998, Week 1 April 1998, Week 5 April 1998, Week 4 April 1998, Week 3 April 1998, Week 2 April 1998, Week 1 March 1998, Week 5 March 1998, Week 4 March 1998, Week 3 March 1998, Week 2 March 1998, Week 1 February 1998, Week 5 February 1998, Week 4 February 1998, Week 3 February 1998, Week 2 February 1998, Week 1 January 1998, Week 5 January 1998, Week 4 January 1998, Week 3 January 1998, Week 2 January 1998, Week 1 December 1997, Week 5 December 1997, Week 4 December 1997, Week 3 December 1997, Week 2 December 1997, Week 1 November 1997, Week 5 November 1997, Week 4 November 1997, Week 3 November 1997, Week 2 November 1997, Week 1 October 1997, Week 5 October 1997, Week 4 October 1997, Week 3 October 1997, Week 2 October 1997, Week 1 September 1997, Week 5 September 1997, Week 4 September 1997, Week 3 September 1997, Week 2 September 1997, Week 1 August 1997, Week 5 August 1997, Week 4 August 1997, Week 3 August 1997, Week 2 August 1997, Week 1 July 1997, Week 5 July 1997, Week 4 July 1997, Week 3 July 1997, Week 2 July 1997, Week 1 June 1997, Week 5 June 1997, Week 4 June 1997, Week 3 June 1997, Week 2 June 1997, Week 1 May 1997, Week 5 May 1997, Week 4 May 1997, Week 3 May 1997, Week 2 May 1997, Week 1 April 1997, Week 5 April 1997, Week 4 April 1997, Week 3 April 1997, Week 2 April 1997, Week 1 March 1997, Week 5 March 1997, Week 4 March 1997, Week 3 March 1997, Week 2 March 1997, Week 1 February 1997, Week 5 February 1997, Week 4 February 1997, Week 3 February 1997, Week 2 February 1997, Week 1 January 1997, Week 5 January 1997, Week 4 January 1997, Week 3 January 1997, Week 2 January 1997, Week 1 December 1996, Week 5 December 1996, Week 4 December 1996, Week 3 December 1996, Week 2 December 1996, Week 1 November 1996, Week 5 November 1996, Week 4 November 1996, Week 3 November 1996, Week 2 November 1996, Week 1 October 1996, Week 5 October 1996, Week 4 October 1996, Week 3 October 1996, Week 2 October 1996, Week 1 September 1996, Week 5 September 1996, Week 4 September 1996, Week 3 September 1996, Week 2 September 1996, Week 1 August 1996, Week 5 August 1996, Week 4 August 1996, Week 3 August 1996, Week 2 August 1996, Week 1 July 1996, Week 5 July 1996, Week 4 July 1996, Week 3 July 1996, Week 2 July 1996, Week 1 June 1996, Week 5 June 1996, Week 4 June 1996, Week 3 June 1996, Week 2 June 1996, Week 1 May 1996, Week 5 May 1996, Week 4 May 1996, Week 3 May 1996, Week 2 May 1996, Week 1 April 1996, Week 5 April 1996, Week 4 April 1996, Week 3 April 1996, Week 2 April 1996, Week 1 March 1996, Week 5 March 1996, Week 4 March 1996, Week 3 March 1996, Week 2 March 1996, Week 1 February 1996, Week 5 February 1996, Week 4 February 1996, Week 3 February 1996, Week 2 February 1996, Week 1 January 1996, Week 5 January 1996, Week 4 January 1996, Week 3 January 1996, Week 2 January 1996, Week 1 December 1995, Week 5 December 1995, Week 4 December 1995, Week 3 December 1995, Week 2 December 1995, Week 1 November 1995, Week 5 November 1995, Week 4 November 1995, Week 3 November 1995, Week 2 November 1995, Week 1 October 1995, Week 5 October 1995, Week 4 October 1995, Week 3 October 1995, Week 2 October 1995, Week 1 September 1995, Week 5 September 1995, Week 4 September 1995, Week 3 September 1995, Week 2 September 1995, Week 1 August 1995, Week 5 August 1995, Week 4 August 1995, Week 3 August 1995, Week 2 August 1995, Week 1 July 1995, Week 5 July 1995, Week 4 July 1995, Week 3 July 1995, Week 2 July 1995, Week 1 June 1995, Week 5 June 1995, Week 4 June 1995, Week 3 June 1995, Week 2 June 1995, Week 1 May 1995, Week 5 May 1995, Week 4 May 1995, Week 3 May 1995, Week 2 May 1995, Week 1 April 1995, Week 5 April 1995, Week 4 April 1995, Week 3 April 1995, Week 2 April 1995, Week 1 March 1995, Week 5 March 1995, Week 4 March 1995, Week 3 March 1995, Week 2 March 1995, Week 1 February 1995, Week 4 February 1995, Week 3 February 1995, Week 2 February 1995, Week 1 January 1995, Week 5 January 1995, Week 4 January 1995, Week 3 January 1995, Week 2 January 1995, Week 1 December 1994, Week 5 December 1994, Week 4 December 1994, Week 3 December 1994, Week 2 December 1994, Week 1 November 1994, Week 5 November 1994, Week 4 November 1994, Week 3 November 1994, Week 2 November 1994, Week 1 October 1994, Week 5 October 1994, Week 4 October 1994, Week 3 October 1994, Week 2 October 1994, Week 1 September 1994, Week 5 September 1994, Week 4 September 1994, Week 3 September 1994, Week 2 September 1994, Week 1 August 1994, Week 5 August 1994, Week 4 August 1994, Week 3 August 1994, Week 2 August 1994, Week 1 July 1994, Week 5 July 1994, Week 4 July 1994, Week 3 July 1994, Week 2 July 1994, Week 1 June 1994, Week 5 June 1994, Week 4 June 1994, Week 3 June 1994, Week 2 June 1994, Week 1 May 1994, Week 5 May 1994, Week 4 May 1994, Week 3 May 1994, Week 2 May 1994, Week 1 April 1994, Week 5 April 1994, Week 4 April 1994, Week 3 April 1994, Week 2 April 1994, Week 1 March 1994, Week 5 March 1994, Week 4 March 1994, Week 3 March 1994, Week 2 March 1994, Week 1 February 1994, Week 4 February 1994, Week 3 February 1994, Week 2 February 1994, Week 1 February 1994 January 1994 December 1993 November 1993
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