This is a multi-part message in MIME format.

--euoliwusevrmhacjdeylcaajnoppeq
Content-Type: text/plain; charset=us-ascii

I had thought I had had no contact with Alan, other than his valued
contributions here on the Parkinson List. But a memory kept tugging at me
and I finally went back into my archived notes of past support group
meetings, and there he was! No wonder it nagged at my memory, for his was
one of the most interesting and informative contributions to our area
support group that I can remember. And he was memorable too. He remains
quite vivid in my memory.  It was just the name that had eluded me.

This was  the evening of May 26,1992 at Pacific College in Fresno,
California. About seventy people were present to hear him tell us about
Duodenal Infusion of Sinemet for Parkinson therapy. He had such a pump and
his use of it during the presentation provided us with a dramatic
demonstration of how rapidly Sinemet could be made available to the brain
when it was delivered directly into the duodenum, bypassing the stomach.

I have included my notes that I scribbled as he spoke to us. Infusion pumps
were developed some twenty years ago to deliver insulin for brittle
diabetics who could not be helped by the usual means. It was adapted
experimentally for Parkinsons, and perhaps other problems, later. I had
forgotten about this method of delivery. Has it been abandoned?

We all will miss Alan so very much. His passing was a very great shock, but
he will remain in our memories.

Martha and Neal Rohrer
[log in to unmask]

--euoliwusevrmhacjdeylcaajnoppeq
Content-Type: application/octet-stream; name="Infuse.asc"
Content-Transfer-Encoding: base64
Content-Disposition: attachment; filename="Infuse.asc"
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--euoliwusevrmhacjdeylcaajnoppeq--