![PARKINSN Archives PARKINSN Archives](/archives/images/b-archiveicon.png) |
PARKINSN Archives
|
PARKINSN@LISTSERV.UTORONTO.CA
|
|
|
|
Charlie Meyer inquires:
>People's reactions do different medications differ widely. There had
>been anecdotal medical reports that Ambien was helpful for PD. This is
>not a double blind study and has no greater validity than the reports of
>benefits to PWP from melatonin. I am aware of some reports of adverse
>effects from melatonin. What happened to you with Ambien? Whether your
>reaction was idiosyncratic or predictable list member should know about
>it since Ambien is being prescribed more widely. If your reaction was
>an unusual one your neurologist (or you) should report it to the FDA.
>What is your source for the statement that "at worst the most highly
>addictive sleep aid yet developed"?
I will do my best to recreate my study, as I did not save the documents that
my statements are based on, except the archives printout on Ambien. From the
list archives on Ambien I quote the following excerpts..."Zolpidem (Ambien)
is only recommended for use in the short-term treatment of insomnia...If
therapy is continued for more than 2 weeks the possibility of a withdrawal
syndrome should be considered and abrupt discontinuation of therapy
avoided......Zolpidem should be used cautiously in patients with major
depression, these patients may become more susceptible to suicidal
ideation....Elderly and/or debilitated patients may be more sensitive to the
effects of zolpidem".
>From the Searle HealthNet page: "Use in the elderly and/or debilitated
patients: Impaired motor and/or cognitive performance after repeated
exposure or unusual sensitivity to sedative/hypnotic drugs is a concern in
the treatment of elderly and/or debilitated patients. "
The following from a medline search on melatonin and Parkinsons:
Life Sci 60 (2): PL23-PL29 (1997)
Melatonin is protective against MPTP-induced striatal and hippocampal lesions.
Acuna-Castroviejo D, Coto-Montes A, Gaia Monti M, Ortiz GG, Reiter RJ
Instituto de Biotecnologia, Universidad de Granada, Spain.
The in vivo effect of melatonin on MPTP-induced neurotoxicity in mouse brain
was studied. Melatonin (10 mg/kg) or saline was administered
intraperitoneally (i.p.) to mice 30 min prior to a s.c. injection of MPTP
(20 mg/kg). After MPTP treatment, the animals received melatonin or saline
injections every hour for three hours. Mice were killed 4 hours after the
MPTP injection. Regionally-specific increases in lipid peroxidation were
observed in corpus striatum and hippocampus (71% and 58%, respectively), but
not in cerebral cortex, cerebellum or midbrain. Treatment with melatonin
completely reversed the rises in lipid peroxidation products. MPTP-treated
mice showed a significant decrease in the striatal tyrosine hydroxylase
immunoreactive nerve terminals, an effect that was also prevented by
melatonin. These data show that melatonin is neuroprotective in this MPTP
model of Parkinson's disease and suggest that melatonin, an endogenous
antioxidant and nontoxic compound, may have potential beneficial effects for
this neurodegenerative disorder.
Also, this hypothesis about the Parkinsonian reduced blink rate interested me:
Int J Neurosci 51 (1-2): 99-103 (Mar 1990)
The significance of eye blink rate in parkinsonism: a hypothesis.
Sandyk R
Department of Psychiatry, College of Physicians & Surgeons, Columbia
University, NY.
Alterations in blink rate have been reported in several neuropsychiatric
disorders presumed to result from abnormal central dopaminergic functions.
Increased blink rate in schizophrenia, Tardive dyskinesia, Tourette's
syndrome and Meige's disease are associated with enhanced dopaminergic
functions. Parkinson's disease is associated with reduced dopaminergic
functions and decreased blink rate. Thus, blink rate may reflect striatal
and mesolimbic dopaminergic activity. Since acute light exposure suppresses
melatonin production and darkness stimulates melatonin secretion, blinking
may serve to regulate light-dark exposure to the pineal gland and thus to
'fine tune' melatonin production. As there is evidence to suggest that
melatonin inhibits the release of dopamine in the striatum and limbic
system, increased blink rate may serve to reduce light exposure, increase
melatonin secretion and attenuate dopaminergic functions. Conversely,
decreased blinking (as is observed in patients with Parkinson's disease)
could reflect a compensatory mechanism to increase light exposure, reduce
melatonin production and ultimately increase dopamine functions. This model
is novel in that for the first time it suggests a functional link among
blink rate, melatonin secretion and striatal dopaminergic functions in
movement disorders.
There is an enormous amount of data regarding the beneficial effect of
melatonin on the reduced electro-magnetic field of the PWP, but I'm not too
up to date on this school of thought.
To address your questions about my adverse reaction to Ambien; I think they
fell right into the warnings noted. Ambien allowed me 6 hours of sleep, no
more or less. That's its window. I had been accustomed to 7-8 hours sleep
most nights taking 1 mg of regular melatonin and 2 mgs of time release
melatonin, so fatigue started to creep up on me quickly. When I saw this
happening, I tried to switch off with melatonin, but found that the
melatonin no longer worked for me. The worst thing was that soon I was
caught in a depression that I hadn't seen coming, and I normally don't have
trouble with depression. By the end of the 2 or so weeks that I used Ambien,
the depression had consumed me and I spent the last 3 days in bed, unable to
initiate any activity, overwhelmed by life. When my husband and I finally
connected this whole mess to the advent of Ambien, I immediately stopped its
use, and rode out the 2 or 3 days it took to start to stabilize sleep again.
As bad as I felt at the very end with such sleep deprivation, I noticed the
depression start to lift and that encouraged me to hang in there. I can only
guess how someone with a history of depression might respond to this drug.
I have learned my lesson...the best intentions of the best doctors still
can't replace having an intelligent approach to my treatment. I understand
that the Parkinsonian sleep disorder is chronic, and Ambien will be a
life-long drug for some, but I would caution anyone using it to be alert for
signs of depression.
Kathie Tollifson
[log in to unmask]
46/8
|
|
|
|
|
Archives |
March 2024, Week 4 January 2022, Week 4 November 2021, Week 4 February 2021, Week 2 December 2020, Week 2 October 2020, Week 4 June 2020, Week 4 May 2020, Week 2 May 2020, Week 1 April 2020, Week 5 April 2020, Week 1 March 2020, Week 5 March 2020, Week 4 March 2020, Week 2 March 2020, Week 1 February 2020, Week 4 February 2020, Week 3 February 2020, Week 1 January 2020, Week 5 January 2020, Week 2 October 2019, Week 1 September 2019, Week 5 September 2019, Week 3 July 2019, Week 1 June 2019, Week 5 June 2019, Week 4 June 2019, Week 3 June 2019, Week 1 April 2019, Week 5 April 2019, Week 4 April 2019, Week 2 March 2019, Week 5 March 2019, Week 3 March 2019, Week 2 March 2019, Week 1 February 2019, Week 4 January 2019, Week 3 January 2019, Week 2 January 2019, Week 1 December 2018, Week 5 December 2018, Week 4 December 2018, Week 2 November 2018, Week 3 November 2018, Week 2 November 2018, Week 1 October 2018, Week 4 October 2018, Week 3 October 2018, Week 1 September 2018, Week 4 September 2018, Week 3 August 2018, Week 4 August 2018, Week 3 August 2018, Week 1 July 2018, Week 4 July 2018, Week 3 July 2018, Week 2 July 2018, Week 1 June 2018, Week 5 June 2018, Week 3 June 2018, Week 1 May 2018, Week 5 May 2018, Week 4 May 2018, Week 3 May 2018, Week 2 May 2018, Week 1 April 2018, Week 4 April 2018, Week 3 April 2018, Week 2 February 2018, Week 3 January 2018, Week 5 January 2018, Week 2 January 2018, Week 1 December 2017, Week 4 December 2017, Week 3 December 2017, Week 1 November 2017, Week 5 November 2017, Week 4 November 2017, Week 3 November 2017, Week 2 November 2017, Week 1 October 2017, Week 4 October 2017, Week 2 October 2017, Week 1 September 2017, Week 5 September 2017, Week 4 September 2017, Week 3 September 2017, Week 2 September 2017, Week 1 August 2017, Week 4 August 2017, Week 2 August 2017, Week 1 July 2017, Week 5 July 2017, Week 4 July 2017, Week 3 July 2017, Week 2 July 2017, Week 1 June 2017, Week 5 June 2017, Week 4 June 2017, Week 3 June 2017, Week 2 June 2017, Week 1 May 2017, Week 5 May 2017, Week 4 May 2017, Week 3 May 2017, Week 2 May 2017, Week 1 April 2017, Week 3 April 2017, Week 2 April 2017, Week 1 March 2017, Week 4 March 2017, Week 3 March 2017, Week 2 March 2017, Week 1 February 2017, Week 3 February 2017, Week 2 February 2017, Week 1 January 2017, Week 4 January 2017, Week 2 January 2017, Week 1 December 2016, Week 5 December 2016, Week 4 December 2016, Week 2 December 2016, Week 1 November 2016, Week 4 November 2016, Week 3 November 2016, Week 2 November 2016, Week 1 October 2016, Week 4 October 2016, Week 3 October 2016, Week 1 September 2016, Week 3 September 2016, Week 2 September 2016, Week 1 August 2016, Week 4 July 2016, Week 5 July 2016, Week 4 July 2016, Week 3 July 2016, Week 2 July 2016, Week 1 June 2016, Week 5 June 2016, Week 3 June 2016, Week 2 June 2016, Week 1 May 2016, Week 5 May 2016, Week 4 May 2016, Week 3 May 2016, Week 2 May 2016, Week 1 April 2016, Week 5 April 2016, Week 4 April 2016, Week 3 April 2016, Week 2 April 2016, Week 1 March 2016, Week 5 March 2016, Week 4 March 2016, Week 3 March 2016, Week 2 March 2016, Week 1 February 2016, Week 5 February 2016, Week 4 February 2016, Week 3 February 2016, Week 2 February 2016, Week 1 January 2016, Week 5 January 2016, Week 4 January 2016, Week 3 January 2016, Week 2 January 2016, Week 1 December 2015, Week 5 December 2015, Week 4 December 2015, Week 3 December 2015, Week 2 December 2015, Week 1 November 2015, Week 5 November 2015, Week 3 November 2015, Week 2 November 2015, Week 1 October 2015, Week 5 October 2015, Week 4 October 2015, Week 3 October 2015, Week 2 October 2015, Week 1 September 2015, Week 5 September 2015, Week 4 September 2015, Week 3 September 2015, Week 2 September 2015, Week 1 August 2015, Week 5 August 2015, Week 4 August 2015, Week 3 August 2015, Week 2 August 2015, Week 1 July 2015, Week 5 July 2015, Week 4 July 2015, Week 3 July 2015, Week 2 July 2015, Week 1 June 2015, Week 5 June 2015, Week 4 June 2015, Week 3 June 2015, Week 2 June 2015, Week 1 May 2015, Week 5 May 2015, Week 4 May 2015, Week 3 May 2015, Week 2 May 2015, Week 1 April 2015, Week 4 April 2015, Week 3 April 2015, Week 2 April 2015, Week 1 March 2015, Week 5 March 2015, Week 4 March 2015, Week 3 March 2015, Week 2 March 2015, Week 1 February 2015, Week 4 February 2015, Week 3 February 2015, Week 2 February 2015, Week 1 January 2015, Week 5 January 2015, Week 4 January 2015, Week 3 January 2015, Week 2 December 2014, Week 5 December 2014, Week 4 December 2014, Week 3 December 2014, Week 2 December 2014, Week 1 November 2014, Week 5 November 2014, Week 4 November 2014, Week 3 November 2014, Week 2 November 2014, Week 1 October 2014, Week 5 October 2014, Week 4 October 2014, Week 3 October 2014, Week 2 October 2014, Week 1 September 2014, Week 5 September 2014, Week 4 September 2014, Week 3 September 2014, Week 2 September 2014, Week 1 August 2014, Week 5 August 2014, Week 4 August 2014, Week 3 August 2014, Week 2 August 2014, Week 1 July 2014, Week 5 July 2014, Week 4 July 2014, Week 3 July 2014, Week 2 July 2014, Week 1 June 2014, Week 5 June 2014, Week 4 June 2014, Week 3 June 2014, Week 2 June 2014, Week 1 May 2014, Week 4 May 2014, Week 3 May 2014, Week 2 May 2014, Week 1 April 2014, Week 5 April 2014, Week 4 April 2014, Week 3 April 2014, Week 2 April 2014, Week 1 March 2014, Week 5 March 2014, Week 4 March 2014, Week 3 March 2014, Week 2 March 2014, Week 1 February 2014, Week 4 February 2014, Week 3 February 2014, Week 2 February 2014, Week 1 January 2014, Week 5 January 2014, Week 4 January 2014, Week 3 January 2014, Week 2 January 2014, Week 1 December 2013, Week 5 December 2013, Week 4 December 2013, Week 3 December 2013, Week 2 December 2013, Week 1 November 2013, Week 4 November 2013, Week 3 November 2013, Week 2 November 2013, Week 1 October 2013, Week 5 October 2013, Week 4 October 2013, Week 3 October 2013, Week 2 October 2013, Week 1 September 2013, Week 5 September 2013, Week 4 September 2013, Week 3 September 2013, Week 2 September 2013, Week 1 August 2013, Week 5 August 2013, Week 4 August 2013, Week 3 August 2013, Week 2 August 2013, Week 1 July 2013, Week 5 July 2013, Week 4 July 2013, Week 3 July 2013, Week 2 July 2013, Week 1 June 2013, Week 5 June 2013, Week 4 June 2013, Week 3 June 2013, Week 2 June 2013, Week 1 May 2013, Week 5 May 2013, Week 4 May 2013, Week 3 May 2013, Week 2 May 2013, Week 1 April 2013, Week 5 April 2013, Week 4 April 2013, Week 3 April 2013, Week 2 April 2013, Week 1 March 2013, Week 5 March 2013, Week 4 March 2013, Week 3 March 2013, Week 2 March 2013, Week 1 February 2013, Week 4 February 2013, Week 3 February 2013, Week 2 February 2013, Week 1 January 2013, Week 5 January 2013, Week 3 January 2013, Week 2 January 2013, Week 1 December 2012, Week 5 December 2012, Week 4 December 2012, Week 3 December 2012, Week 2 December 2012, Week 1 November 2012, Week 5 November 2012, Week 3 November 2012, Week 2 November 2012, Week 1 October 2012, Week 5 October 2012, Week 4 October 2012, Week 3 October 2012, Week 2 October 2012, Week 1 September 2012, Week 5 September 2012, Week 4 September 2012, Week 3 September 2012, Week 2 September 2012, Week 1 August 2012, Week 5 August 2012, Week 4 August 2012, Week 3 August 2012, Week 2 August 2012, Week 1 July 2012, Week 5 July 2012, Week 4 July 2012, Week 3 July 2012, Week 2 July 2012, Week 1 June 2012, Week 5 June 2012, Week 4 June 2012, Week 3 June 2012, Week 2 June 2012, Week 1 May 2012, Week 5 May 2012, Week 4 May 2012, Week 3 May 2012, Week 2 May 2012, Week 1 April 2012, Week 5 April 2012, Week 4 April 2012, Week 3 April 2012, Week 2 April 2012, Week 1 March 2012, Week 5 March 2012, Week 4 March 2012, Week 3 March 2012, Week 2 March 2012, Week 1 February 2012, Week 5 February 2012, Week 4 February 2012, Week 3 February 2012, Week 2 February 2012, Week 1 January 2012, Week 5 January 2012, Week 4 January 2012, Week 3 January 2012, Week 2 January 2012, Week 1 December 2011, Week 5 December 2011, Week 4 December 2011, Week 3 December 2011, Week 2 December 2011, Week 1 November 2011, Week 5 November 2011, Week 4 November 2011, Week 3 November 2011, Week 2 November 2011, Week 1 October 2011, Week 5 October 2011, Week 4 October 2011, Week 3 October 2011, Week 2 October 2011, Week 1 September 2011, Week 5 September 2011, Week 4 September 2011, Week 3 September 2011, Week 2 September 2011, Week 1 August 2011, Week 5 August 2011, Week 4 August 2011, Week 3 August 2011, Week 2 August 2011, Week 1 July 2011, Week 5 July 2011, Week 4 July 2011, Week 3 July 2011, Week 2 July 2011, Week 1 June 2011, Week 5 June 2011, Week 4 June 2011, Week 3 June 2011, Week 2 June 2011, Week 1 May 2011, Week 5 May 2011, Week 4 May 2011, Week 3 May 2011, Week 2 May 2011, Week 1 April 2011, Week 5 April 2011, Week 4 April 2011, Week 3 April 2011, Week 2 April 2011, Week 1 March 2011, Week 5 March 2011, Week 4 March 2011, Week 3 March 2011, Week 2 March 2011, Week 1 February 2011, Week 4 February 2011, Week 3 February 2011, Week 2 February 2011, Week 1 January 2011, Week 5 January 2011, Week 4 January 2011, Week 3 January 2011, Week 2 January 2011, Week 1 December 2010, Week 5 December 2010, Week 4 December 2010, Week 3 December 2010, Week 2 December 2010, Week 1 November 2010, Week 5 November 2010, Week 4 November 2010, Week 3 November 2010, Week 2 November 2010, Week 1 October 2010, Week 5 October 2010, Week 4 October 2010, Week 3 October 2010, Week 2 October 2010, Week 1 September 2010, Week 5 September 2010, Week 4 September 2010, Week 3 September 2010, Week 2 September 2010, Week 1 August 2010, Week 5 August 2010, Week 4 August 2010, Week 3 August 2010, Week 2 August 2010, Week 1 July 2010, Week 5 July 2010, Week 4 July 2010, Week 3 July 2010, Week 2 July 2010, Week 1 June 2010, Week 5 June 2010, Week 4 June 2010, Week 3 June 2010, Week 2 June 2010, Week 1 May 2010, Week 5 May 2010, Week 4 May 2010, Week 3 May 2010, Week 2 May 2010, Week 1 April 2010, Week 5 April 2010, Week 4 April 2010, Week 3 April 2010, Week 2 April 2010, Week 1 March 2010, Week 5 March 2010, Week 4 March 2010, Week 3 March 2010, Week 2 March 2010, Week 1 February 2010, Week 4 February 2010, Week 3 February 2010, Week 2 February 2010, Week 1 January 2010, Week 5 January 2010, Week 4 January 2010, Week 3 January 2010, Week 2 January 2010, Week 1 December 2009, Week 5 December 2009, Week 4 December 2009, Week 3 December 2009, Week 2 December 2009, Week 1 November 2009, Week 5 November 2009, Week 4 November 2009, Week 3 November 2009, Week 2 November 2009, Week 1 October 2009, Week 5 October 2009, Week 4 October 2009, Week 3 October 2009, Week 2 October 2009, Week 1 September 2009, Week 5 September 2009, Week 4 September 2009, Week 3 September 2009, Week 2 September 2009, Week 1 August 2009, Week 5 August 2009, Week 4 August 2009, Week 3 August 2009, Week 2 August 2009, Week 1 July 2009, Week 5 July 2009, Week 4 July 2009, Week 3 July 2009, Week 2 July 2009, Week 1 June 2009, Week 5 June 2009, Week 4 June 2009, Week 3 June 2009, Week 2 June 2009, Week 1 May 2009, Week 5 May 2009, Week 4 May 2009, Week 3 May 2009, Week 2 May 2009, Week 1 April 2009, Week 5 April 2009, Week 4 April 2009, Week 3 April 2009, Week 2 April 2009, Week 1 March 2009, Week 5 March 2009, Week 4 March 2009, Week 3 March 2009, Week 2 March 2009, Week 1 February 2009, Week 4 February 2009, Week 3 February 2009, Week 2 February 2009, Week 1 January 2009, Week 5 January 2009, Week 4 January 2009, Week 3 January 2009, Week 2 January 2009, Week 1 December 2008, Week 5 December 2008, Week 4 December 2008, Week 3 December 2008, Week 2 December 2008, Week 1 November 2008, Week 5 November 2008, Week 4 November 2008, Week 3 November 2008, Week 2 November 2008, Week 1 October 2008, Week 5 October 2008, Week 4 October 2008, Week 3 October 2008, Week 2 October 2008, Week 1 September 2008, Week 5 September 2008, Week 4 September 2008, Week 3 September 2008, Week 2 September 2008, Week 1 August 2008, Week 5 August 2008, Week 4 August 2008, Week 3 August 2008, Week 2 August 2008, Week 1 July 2008, Week 5 July 2008, Week 4 July 2008, Week 3 July 2008, Week 2 July 2008, Week 1 June 2008, Week 5 June 2008, Week 4 June 2008, Week 3 June 2008, Week 2 June 2008, Week 1 May 2008, Week 5 May 2008, Week 4 May 2008, Week 3 May 2008, Week 2 May 2008, Week 1 April 2008, Week 5 April 2008, Week 4 April 2008, Week 3 April 2008, Week 2 April 2008, Week 1 March 2008, Week 5 March 2008, Week 4 March 2008, Week 3 March 2008, Week 2 March 2008, Week 1 February 2008, Week 5 February 2008, Week 4 February 2008, Week 3 February 2008, Week 2 February 2008, Week 1 January 2008, Week 5 January 2008, Week 4 January 2008, Week 3 January 2008, Week 2 January 2008, Week 1 December 2007, Week 5 December 2007, Week 4 December 2007, Week 3 December 2007, Week 2 December 2007, Week 1 November 2007, Week 5 November 2007, Week 4 November 2007, Week 3 November 2007, Week 2 November 2007, Week 1 October 2007, Week 5 October 2007, Week 4 October 2007, Week 3 October 2007, Week 2 October 2007, Week 1 September 2007, Week 5 September 2007, Week 4 September 2007, Week 3 September 2007, Week 2 September 2007, Week 1 August 2007, Week 5 August 2007, Week 4 August 2007, Week 3 August 2007, Week 2 August 2007, Week 1 July 2007, Week 5 July 2007, Week 4 July 2007, Week 3 July 2007, Week 2 July 2007, Week 1 June 2007, Week 5 June 2007, Week 4 June 2007, Week 3 June 2007, Week 2 June 2007, Week 1 May 2007, Week 5 May 2007, Week 4 May 2007, Week 3 May 2007, Week 2 May 2007, Week 1 April 2007, Week 5 April 2007, Week 4 April 2007, Week 3 April 2007, Week 2 April 2007, Week 1 March 2007, Week 5 March 2007, Week 4 March 2007, Week 3 March 2007, Week 2 March 2007, Week 1 February 2007, Week 4 February 2007, Week 3 February 2007, Week 2 February 2007, Week 1 January 2007, Week 5 January 2007, Week 4 January 2007, Week 3 January 2007, Week 2 January 2007, Week 1 December 2006, Week 5 December 2006, Week 4 December 2006, Week 3 December 2006, Week 2 December 2006, Week 1 November 2006, Week 5 November 2006, Week 4 November 2006, Week 3 November 2006, Week 2 November 2006, Week 1 October 2006, Week 5 October 2006, Week 4 October 2006, Week 3 October 2006, Week 2 October 2006, Week 1 September 2006, Week 5 September 2006, Week 4 September 2006, Week 3 September 2006, Week 2 September 2006, Week 1 August 2006, Week 5 August 2006, Week 4 August 2006, Week 3 August 2006, Week 2 August 2006, Week 1 July 2006, Week 5 July 2006, Week 4 July 2006, Week 3 July 2006, Week 2 July 2006, Week 1 June 2006, Week 5 June 2006, Week 4 June 2006, Week 3 June 2006, Week 2 June 2006, Week 1 May 2006, Week 5 May 2006, Week 4 May 2006, Week 3 May 2006, Week 2 May 2006, Week 1 April 2006, Week 5 April 2006, Week 4 April 2006, Week 3 April 2006, Week 2 April 2006, Week 1 March 2006, Week 5 March 2006, Week 4 March 2006, Week 3 March 2006, Week 2 March 2006, Week 1 February 2006, Week 4 February 2006, Week 3 February 2006, Week 2 February 2006, Week 1 January 2006, Week 5 January 2006, Week 4 January 2006, Week 3 January 2006, Week 2 January 2006, Week 1 December 2005, Week 5 December 2005, Week 4 December 2005, Week 3 December 2005, Week 2 December 2005, Week 1 November 2005, Week 5 November 2005, Week 4 November 2005, Week 3 November 2005, Week 2 November 2005, Week 1 October 2005, Week 5 October 2005, Week 4 October 2005, Week 3 October 2005, Week 2 October 2005, Week 1 September 2005, Week 5 September 2005, Week 4 September 2005, Week 3 September 2005, Week 2 September 2005, Week 1 August 2005, Week 5 August 2005, Week 4 August 2005, Week 3 August 2005, Week 2 August 2005, Week 1 July 2005, Week 5 July 2005, Week 4 July 2005, Week 3 July 2005, Week 2 July 2005, Week 1 June 2005, Week 5 June 2005, Week 4 June 2005, Week 3 June 2005, Week 2 June 2005, Week 1 May 2005, Week 5 May 2005, Week 4 May 2005, Week 3 May 2005, Week 2 May 2005, Week 1 April 2005, Week 5 April 2005, Week 4 April 2005, Week 3 April 2005, Week 2 April 2005, Week 1 March 2005, Week 5 March 2005, Week 4 March 2005, Week 3 March 2005, Week 2 March 2005, Week 1 February 2005, Week 4 February 2005, Week 3 February 2005, Week 2 February 2005, Week 1 January 2005, Week 5 January 2005, Week 4 January 2005, Week 3 January 2005, Week 2 January 2005, Week 1 December 2004, Week 5 December 2004, Week 4 December 2004, Week 3 December 2004, Week 2 December 2004, Week 1 November 2004, Week 5 November 2004, Week 4 November 2004, Week 3 November 2004, Week 2 November 2004, Week 1 October 2004, Week 5 October 2004, Week 4 October 2004, Week 3 October 2004, Week 2 October 2004, Week 1 September 2004, Week 5 September 2004, Week 4 September 2004, Week 3 September 2004, Week 2 September 2004, Week 1 August 2004, Week 5 August 2004, Week 4 August 2004, Week 3 August 2004, Week 2 August 2004, Week 1 July 2004, Week 5 July 2004, Week 4 July 2004, Week 3 July 2004, Week 2 July 2004, Week 1 June 2004, Week 5 June 2004, Week 4 June 2004, Week 3 June 2004, Week 2 June 2004, Week 1 May 2004, Week 5 May 2004, Week 4 May 2004, Week 3 May 2004, Week 2 May 2004, Week 1 April 2004, Week 5 April 2004, Week 4 April 2004, Week 3 April 2004, Week 2 April 2004, Week 1 March 2004, Week 5 March 2004, Week 4 March 2004, Week 3 March 2004, Week 2 March 2004, Week 1 February 2004, Week 5 February 2004, Week 4 February 2004, Week 3 February 2004, Week 2 February 2004, Week 1 January 2004, Week 5 January 2004, Week 4 January 2004, Week 3 January 2004, Week 2 January 2004, Week 1 December 2003, Week 5 December 2003, Week 4 December 2003, Week 3 December 2003, Week 2 December 2003, Week 1 November 2003, Week 5 November 2003, Week 4 November 2003, Week 3 November 2003, Week 2 November 2003, Week 1 October 2003, Week 5 October 2003, Week 4 October 2003, Week 3 October 2003, Week 2 October 2003, Week 1 September 2003, Week 5 September 2003, Week 4 September 2003, Week 3 September 2003, Week 2 September 2003, Week 1 August 2003, Week 5 August 2003, Week 4 August 2003, Week 3 August 2003, Week 2 August 2003, Week 1 July 2003, Week 5 July 2003, Week 4 July 2003, Week 3 July 2003, Week 2 July 2003, Week 1 June 2003, Week 5 June 2003, Week 4 June 2003, Week 3 June 2003, Week 2 June 2003, Week 1 May 2003, Week 5 May 2003, Week 4 May 2003, Week 3 May 2003, Week 2 May 2003, Week 1 April 2003, Week 5 April 2003, Week 4 April 2003, Week 3 April 2003, Week 2 April 2003, Week 1 March 2003, Week 5 March 2003, Week 4 March 2003, Week 3 March 2003, Week 2 March 2003, Week 1 February 2003, Week 4 February 2003, Week 3 February 2003, Week 2 February 2003, Week 1 January 2003, Week 5 January 2003, Week 4 January 2003, Week 3 January 2003, Week 2 January 2003, Week 1 December 2002, Week 5 December 2002, Week 4 December 2002, Week 3 December 2002, Week 2 December 2002, Week 1 November 2002, Week 5 November 2002, Week 4 November 2002, Week 3 November 2002, Week 2 November 2002, Week 1 October 2002, Week 5 October 2002, Week 4 October 2002, Week 3 October 2002, Week 2 October 2002, Week 1 September 2002, Week 5 September 2002, Week 4 September 2002, Week 3 September 2002, Week 2 September 2002, Week 1 August 2002, Week 5 August 2002, Week 4 August 2002, Week 3 August 2002, Week 2 August 2002, Week 1 July 2002, Week 5 July 2002, Week 4 July 2002, Week 3 July 2002, Week 2 July 2002, Week 1 June 2002, Week 5 June 2002, Week 4 June 2002, Week 3 June 2002, Week 2 June 2002, Week 1 May 2002, Week 5 May 2002, Week 4 May 2002, Week 3 May 2002, Week 2 May 2002, Week 1 April 2002, Week 5 April 2002, Week 4 April 2002, Week 3 April 2002, Week 2 April 2002, Week 1 March 2002, Week 5 March 2002, Week 4 March 2002, Week 3 March 2002, Week 2 March 2002, Week 1 February 2002, Week 4 February 2002, Week 3 February 2002, Week 2 February 2002, Week 1 January 2002, Week 5 January 2002, Week 4 January 2002, Week 3 January 2002, Week 2 January 2002, Week 1 December 2001, Week 5 December 2001, Week 4 December 2001, Week 3 December 2001, Week 2 December 2001, Week 1 November 2001, Week 5 November 2001, Week 4 November 2001, Week 3 November 2001, Week 2 November 2001, Week 1 October 2001, Week 5 October 2001, Week 4 October 2001, Week 3 October 2001, Week 2 October 2001, Week 1 September 2001, Week 5 September 2001, Week 4 September 2001, Week 3 September 2001, Week 2 September 2001, Week 1 August 2001, Week 5 August 2001, Week 4 August 2001, Week 3 August 2001, Week 2 August 2001, Week 1 July 2001, Week 5 July 2001, Week 4 July 2001, Week 3 July 2001, Week 2 July 2001, Week 1 June 2001, Week 5 June 2001, Week 4 June 2001, Week 3 June 2001, Week 2 June 2001, Week 1 May 2001, Week 5 May 2001, Week 4 May 2001, Week 3 May 2001, Week 2 May 2001, Week 1 April 2001, Week 5 April 2001, Week 4 April 2001, Week 3 April 2001, Week 2 April 2001, Week 1 March 2001, Week 5 March 2001, Week 4 March 2001, Week 3 March 2001, Week 2 March 2001, Week 1 February 2001, Week 4 February 2001, Week 3 February 2001, Week 2 February 2001, Week 1 January 2001, Week 5 January 2001, Week 4 January 2001, Week 3 January 2001, Week 2 January 2001, Week 1 December 2000, Week 5 December 2000, Week 4 December 2000, Week 3 December 2000, Week 2 December 2000, Week 1 November 2000, Week 5 November 2000, Week 4 November 2000, Week 3 November 2000, Week 2 November 2000, Week 1 October 2000, Week 5 October 2000, Week 4 October 2000, Week 3 October 2000, Week 2 October 2000, Week 1 September 2000, Week 5 September 2000, Week 4 September 2000, Week 3 September 2000, Week 2 September 2000, Week 1 August 2000, Week 5 August 2000, Week 4 August 2000, Week 3 August 2000, Week 2 August 2000, Week 1 July 2000, Week 5 July 2000, Week 4 July 2000, Week 3 July 2000, Week 2 July 2000, Week 1 June 2000, Week 5 June 2000, Week 4 June 2000, Week 3 June 2000, Week 2 June 2000, Week 1 May 2000, Week 5 May 2000, Week 4 May 2000, Week 3 May 2000, Week 2 May 2000, Week 1 April 2000, Week 5 April 2000, Week 4 April 2000, Week 3 April 2000, Week 2 April 2000, Week 1 March 2000, Week 5 March 2000, Week 4 March 2000, Week 3 March 2000, Week 2 March 2000, Week 1 February 2000, Week 5 February 2000, Week 4 February 2000, Week 3 February 2000, Week 2 February 2000, Week 1 January 2000, Week 5 January 2000, Week 4 January 2000, Week 3 January 2000, Week 2 January 2000, Week 1 December 1999, Week 5 December 1999, Week 4 December 1999, Week 3 December 1999, Week 2 December 1999, Week 1 November 1999, Week 5 November 1999, Week 4 November 1999, Week 3 November 1999, Week 2 November 1999, Week 1 October 1999, Week 5 October 1999, Week 4 October 1999, Week 3 October 1999, Week 2 October 1999, Week 1 September 1999, Week 5 September 1999, Week 4 September 1999, Week 3 September 1999, Week 2 September 1999, Week 1 August 1999, Week 5 August 1999, Week 4 August 1999, Week 3 August 1999, Week 2 August 1999, Week 1 July 1999, Week 5 July 1999, Week 4 July 1999, Week 3 July 1999, Week 2 July 1999, Week 1 June 1999, Week 5 June 1999, Week 4 June 1999, Week 3 June 1999, Week 2 June 1999, Week 1 May 1999, Week 5 May 1999, Week 4 May 1999, Week 3 May 1999, Week 2 May 1999, Week 1 April 1999, Week 5 April 1999, Week 4 April 1999, Week 3 April 1999, Week 2 April 1999, Week 1 March 1999, Week 5 March 1999, Week 4 March 1999, Week 3 March 1999, Week 2 March 1999, Week 1 February 1999, Week 4 February 1999, Week 3 February 1999, Week 2 February 1999, Week 1 January 1999, Week 5 January 1999, Week 4 January 1999, Week 3 January 1999, Week 2 January 1999, Week 1 December 1998, Week 5 December 1998, Week 4 December 1998, Week 3 December 1998, Week 2 December 1998, Week 1 November 1998, Week 5 November 1998, Week 4 November 1998, Week 3 November 1998, Week 2 November 1998, Week 1 October 1998, Week 5 October 1998, Week 4 October 1998, Week 3 October 1998, Week 2 October 1998, Week 1 September 1998, Week 5 September 1998, Week 4 September 1998, Week 3 September 1998, Week 2 September 1998, Week 1 August 1998, Week 5 August 1998, Week 4 August 1998, Week 3 August 1998, Week 2 August 1998, Week 1 July 1998, Week 5 July 1998, Week 4 July 1998, Week 3 July 1998, Week 2 July 1998, Week 1 June 1998, Week 5 June 1998, Week 4 June 1998, Week 3 June 1998, Week 2 June 1998, Week 1 May 1998, Week 5 May 1998, Week 4 May 1998, Week 3 May 1998, Week 2 May 1998, Week 1 April 1998, Week 5 April 1998, Week 4 April 1998, Week 3 April 1998, Week 2 April 1998, Week 1 March 1998, Week 5 March 1998, Week 4 March 1998, Week 3 March 1998, Week 2 March 1998, Week 1 February 1998, Week 5 February 1998, Week 4 February 1998, Week 3 February 1998, Week 2 February 1998, Week 1 January 1998, Week 5 January 1998, Week 4 January 1998, Week 3 January 1998, Week 2 January 1998, Week 1 December 1997, Week 5 December 1997, Week 4 December 1997, Week 3 December 1997, Week 2 December 1997, Week 1 November 1997, Week 5 November 1997, Week 4 November 1997, Week 3 November 1997, Week 2 November 1997, Week 1 October 1997, Week 5 October 1997, Week 4 October 1997, Week 3 October 1997, Week 2 October 1997, Week 1 September 1997, Week 5 September 1997, Week 4 September 1997, Week 3 September 1997, Week 2 September 1997, Week 1 August 1997, Week 5 August 1997, Week 4 August 1997, Week 3 August 1997, Week 2 August 1997, Week 1 July 1997, Week 5 July 1997, Week 4 July 1997, Week 3 July 1997, Week 2 July 1997, Week 1 June 1997, Week 5 June 1997, Week 4 June 1997, Week 3 June 1997, Week 2 June 1997, Week 1 May 1997, Week 5 May 1997, Week 4 May 1997, Week 3 May 1997, Week 2 May 1997, Week 1 April 1997, Week 5 April 1997, Week 4 April 1997, Week 3 April 1997, Week 2 April 1997, Week 1 March 1997, Week 5 March 1997, Week 4 March 1997, Week 3 March 1997, Week 2 March 1997, Week 1 February 1997, Week 5 February 1997, Week 4 February 1997, Week 3 February 1997, Week 2 February 1997, Week 1 January 1997, Week 5 January 1997, Week 4 January 1997, Week 3 January 1997, Week 2 January 1997, Week 1 December 1996, Week 5 December 1996, Week 4 December 1996, Week 3 December 1996, Week 2 December 1996, Week 1 November 1996, Week 5 November 1996, Week 4 November 1996, Week 3 November 1996, Week 2 November 1996, Week 1 October 1996, Week 5 October 1996, Week 4 October 1996, Week 3 October 1996, Week 2 October 1996, Week 1 September 1996, Week 5 September 1996, Week 4 September 1996, Week 3 September 1996, Week 2 September 1996, Week 1 August 1996, Week 5 August 1996, Week 4 August 1996, Week 3 August 1996, Week 2 August 1996, Week 1 July 1996, Week 5 July 1996, Week 4 July 1996, Week 3 July 1996, Week 2 July 1996, Week 1 June 1996, Week 5 June 1996, Week 4 June 1996, Week 3 June 1996, Week 2 June 1996, Week 1 May 1996, Week 5 May 1996, Week 4 May 1996, Week 3 May 1996, Week 2 May 1996, Week 1 April 1996, Week 5 April 1996, Week 4 April 1996, Week 3 April 1996, Week 2 April 1996, Week 1 March 1996, Week 5 March 1996, Week 4 March 1996, Week 3 March 1996, Week 2 March 1996, Week 1 February 1996, Week 5 February 1996, Week 4 February 1996, Week 3 February 1996, Week 2 February 1996, Week 1 January 1996, Week 5 January 1996, Week 4 January 1996, Week 3 January 1996, Week 2 January 1996, Week 1 December 1995, Week 5 December 1995, Week 4 December 1995, Week 3 December 1995, Week 2 December 1995, Week 1 November 1995, Week 5 November 1995, Week 4 November 1995, Week 3 November 1995, Week 2 November 1995, Week 1 October 1995, Week 5 October 1995, Week 4 October 1995, Week 3 October 1995, Week 2 October 1995, Week 1 September 1995, Week 5 September 1995, Week 4 September 1995, Week 3 September 1995, Week 2 September 1995, Week 1 August 1995, Week 5 August 1995, Week 4 August 1995, Week 3 August 1995, Week 2 August 1995, Week 1 July 1995, Week 5 July 1995, Week 4 July 1995, Week 3 July 1995, Week 2 July 1995, Week 1 June 1995, Week 5 June 1995, Week 4 June 1995, Week 3 June 1995, Week 2 June 1995, Week 1 May 1995, Week 5 May 1995, Week 4 May 1995, Week 3 May 1995, Week 2 May 1995, Week 1 April 1995, Week 5 April 1995, Week 4 April 1995, Week 3 April 1995, Week 2 April 1995, Week 1 March 1995, Week 5 March 1995, Week 4 March 1995, Week 3 March 1995, Week 2 March 1995, Week 1 February 1995, Week 4 February 1995, Week 3 February 1995, Week 2 February 1995, Week 1 January 1995, Week 5 January 1995, Week 4 January 1995, Week 3 January 1995, Week 2 January 1995, Week 1 December 1994, Week 5 December 1994, Week 4 December 1994, Week 3 December 1994, Week 2 December 1994, Week 1 November 1994, Week 5 November 1994, Week 4 November 1994, Week 3 November 1994, Week 2 November 1994, Week 1 October 1994, Week 5 October 1994, Week 4 October 1994, Week 3 October 1994, Week 2 October 1994, Week 1 September 1994, Week 5 September 1994, Week 4 September 1994, Week 3 September 1994, Week 2 September 1994, Week 1 August 1994, Week 5 August 1994, Week 4 August 1994, Week 3 August 1994, Week 2 August 1994, Week 1 July 1994, Week 5 July 1994, Week 4 July 1994, Week 3 July 1994, Week 2 July 1994, Week 1 June 1994, Week 5 June 1994, Week 4 June 1994, Week 3 June 1994, Week 2 June 1994, Week 1 May 1994, Week 5 May 1994, Week 4 May 1994, Week 3 May 1994, Week 2 May 1994, Week 1 April 1994, Week 5 April 1994, Week 4 April 1994, Week 3 April 1994, Week 2 April 1994, Week 1 March 1994, Week 5 March 1994, Week 4 March 1994, Week 3 March 1994, Week 2 March 1994, Week 1 February 1994, Week 4 February 1994, Week 3 February 1994, Week 2 February 1994, Week 1 February 1994 January 1994 December 1993 November 1993
|
|
|
|