Automatic digest processor wrote:
>
> There are 22 messages totalling 5244 lines in this issue.
>
> Topics in this special issue:
>
>   1. Please STOP filling the PD Digest with LENGTHY UNREADABLE CODE!!! (3)
>   2. Martial arts and PD.
>   3. Answers to prayer for Mel
>   4. Pictures,Pictures,Pictures! + More
>   5. Stan's Pallidotomy
>   6. Anything in toenails?
>   7. Robert Langer Meds
>   8. Drug Trials -Reply (2)
>   9. Peter's neuro-clinic visit
>  10. Photography tips/Photos of Phila.
>  11. Glossary &  Humor
>  12. Pictures,Pictures,Pictures!
>  13. Selegiline -Reply (2)
>  14. Introduction
>  15. Mirapex or not
>  16. Possible Mirapex Problem?
>  17. seligiline-reply
>  18. PHOTO
>
> ----------------------------------------------------------------------
>
> Date:    Mon, 27 Oct 1997 20:16:05 -0500
> From:    David Moreland <[log in to unmask]>
> Subject: Re: Please STOP filling the PD Digest with LENGTHY UNREADABLE CODE!!!
>
> At 02:26 PM 10/27/97 -0500, SJS-OnTheNet wrote:
> >***** To All: *****
> >
> >I would like to request that ANOTHER method-- perhaps a "PARALLEL
> >LISTSERV" (perhaps call it "PD Digest-II") -- be established to carry all
> >those pages upon pages of ENCODED items that too often (including in this
> >past issue) FILL UP the PD Digest!
> >
> >What a NUISANCE it is to have to scroll past pages & pages & yet more
> >pages of CODE, just to see if there's any useful humanly READABLE material
> >posted!
> >
>
> Why don't you just use the delete button for those pages & pages & yet more
> pages.
>
> Yours and His
>
> David L. Moreland
> [log in to unmask]
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 20:29:59 -0500
> From:    David Moreland <[log in to unmask]>
> Subject: Martial arts and PD.
>
> Listers,
> Has anyone on this list used any martial arts techniques to provide at
> least little snippets of relief for PD symptoms? My speech threapist
> suggested this topic to me because she is doing some research in this area.
>
> Yours and His
>
> David L. Moreland
> [log in to unmask]
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 20:49:35 -0500
> From:    Mary Ulmer <[log in to unmask]>
> Subject: Answers to prayer for Mel
>
> Four nights ago I was very despondent over Mel's going on Dialysis.  He is
> back home and Dialysis has been delayed due to a better Creatinine Clearance
> test.  Maybe in 2 months he might start dialysis but who knows, maybe never..
> Mel had asked for a "small miracle"---he got a bigger one.  We have felt the
> concern of many friends including our cyberfriends.
> We received many posts of your support and promise of prayers.  We read each
> and were strengthen by them.
> I plan to post off the list to each reponse--hope i don't leave anyone out.
>  We were overwhelmed with the response and certainly feel your prayers were
> answered.  Thank each of you very much.  Things look much brighter and of
> course with some time to reflect, there are worse things than dialysis--just
> another hurdle in this life adventure.
> Love from both of us
> Mary and Mel      Mary CG for Mel 76/11    [log in to unmask]
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 21:03:03 -0500
> From:    Barbara Patterson <[log in to unmask]>
> Subject: Re: Pictures,Pictures,Pictures! + More
>
> Hi...about pictures/attachments.. Some of our members are limited by
> their service providers as to the size of emails they can receive.  Most
> graphics files are quite large.  Multiply the size of one file x the
> number of files sent and we would definitely all have problems.
> Distributing the one file today caused numerous error messages.  (Those
> of you who did not receive the picture file...your server bounced it back
> to me as an error file.)  Also, I don't own a scanner and would have no
> way of handling the picture files so that sort of shoots down the idea
> that I would distribute the files.  Sorry about that.  For the time
> being, we will just have to imagine what each other looks like...
>
> About attachments...many of our members do not have the skills to extract
> these...on some systems there are many, many steps to this process.
> That's why I have suggested sending the message as plain text.  (The KISS
> principle.)
>
> About the way the messages are compiled for the digest...this is all done
> by the listserver at UofT...since this entire service is offered free of
> charge by UofT....  BTW...those 'list funds' that were mentioned in a
> previous message..there aren't any.  UofT allows us to use their system
> free of charge and I volunteer my ?free? time as do John Cottingham and
> Camilla and all the others who help.  I guess you could call it all a
> 'labour of love' or a truly grassroots movement.  The only payment I
> receive is the knowledge that info about pd is available to all who want
> or need it and that none of our members need to feel alone...not with a
> 1600 member cyberfamily.
>
> One more reminder....please do NOT include the entire message to which you
> are replying.  One reason is that it is not necessary and unnecessarily
> clutters up the list.  Another reason is that, if you include the line in
> the original message that points to the parkinsn list, sometimes the
> listserver bounces it back to me as an error message (looping message).
> Sometimes I catch them but with dozens & dozens of error messages every
> day, sometimes I don't.  So your message never gets posted.
>
> (To Janet Paterson who plans to move soon from Bermuda to Ottawa,
> Ontario, Canada...that region received 30 cm of snow today. :)
>
> Barb
>
> ============================================================================
> Barbara Patterson                               [log in to unmask]
> HSC 2J22                                        905-525-9140, ext. 22403
>                         School of Nursing
> ============================================================================
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 21:04:10 -0500
> From:    Camilla Flintermann <[log in to unmask]>
> Subject: Re: Stan's Pallidotomy
>
> Hey Stan-- that novel sounds promising, and lets hope the nurse has
> good sense and gives you the green light for the surgery--best of luck!
>
> Camilla Flintermann, CG for Peter, 79/8, Oxford,Ohio
> [log in to unmask]
> *   *   *   *   *   *   *   *   *   *   *   *   *   *
> "Ask me about the CARE list for PD caregivers!"
> *   *   *   *   *   *   *   *   *   *   *   *   *   *
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 21:09:02 -0500
> From:    Den Gen <[log in to unmask]>
> Subject: Re: Anything in toenails?
>
> Keep us posted--it sounds  very weird but don't they make jello out of horse
> toe nails...hooves!!??
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 21:09:20 -0500
> From:    Mary Ulmer <[log in to unmask]>
> Subject: Re: Robert Langer Meds
>
> Hi-Mel has just the opposite reaction with his sleep patterns.  He is now
> sleeping all night most nights (could be related to his kidney disease i
> suppose however).  I thinking about changing my night aide on the weekends to
> daytime as I now get enought rest myself.
> He is on Mirapex .625 three times daily and has cut the sinemet down from 4
> 50/200 CR to 3 sinemet 25/100CR.  He has an antsy time around 4-6pm and I
> think it may be his 2pm sinemet.
> Mary CG Mel 76/11    [log in to unmask]
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 21:16:37 -0500
> From:    Jeff Jones <[log in to unmask]>
> Subject: Re: Please STOP filling the PD Digest with LENGTHY UNREADABLE CODE!!!
>
> At 02:26 PM 10/27/97 -0500, you wrote:
> >***** To All: *****
> >
> >I would like to request that ANOTHER method-- perhaps a "PARALLEL
> >LISTSERV" (perhaps call it "PD Digest-II") -- be established to carry all
> >those pages upon pages of ENCODED items that too often (including in this
> >past issue) FILL UP the PD Digest!
> >
> >What a NUISANCE it is to have to scroll past pages & pages & yet more
> >pages of CODE, just to see if there's any useful humanly READABLE material
> >posted!
> >
> <---- snip ---->
>
> I have, in the past, subscribed to a number of ListServs and received my
> mail in digest form.  My research into this issue pointed toward a
> "feature" of Microsoft's mail package (Microsoft mail).  The encoded
> information, to my knowledge is not at all within the control of the
> ListServ program.  It is freely tendered by the mail program.  I suspect
> many of you find oddly encoded files in your mail program's download
> folder, or wherever attachments are saved (unless you delete them).  The
> fix is at the source of the mail, not the ListServ.  The MS mail program
> can be modified via the options to prevent the extra mail, but I don't
> remember how because I don't use that package.  The bottom line, page down
> quickly, or set your mail in the parkinsns List to NoDigest and deal with
> the encoded messages individually.
>
> Take care,
> Jeff Jones, PT CG for Becky
> [log in to unmask]
>
> ------------------------------
>
> Date:    Fri, 24 Oct 1997 15:14:37 -0400
> From:    Stephan Schwartz <[log in to unmask]>
> Subject: Drug Trials -Reply
>
> On 10/24 Brian Collins wrote:
> >>>. . . Remacemide . . . drug trials in the U.S. . . . . anyone
> taking part in a trial?<<<
> Hi Brian:
>      One of the 10+ centers conducting a clinical trial of
> remacemide hydrocholride is The Columbia-Presbyterian
> Medical Center in NYC.  The study will last 6 weeks.
>      Researchers report that this medication inhibits the
> glutamine cells of the basel ganglia (the center of motor
> control of the brain).  Researchers are trying to determine if
> remacemide can alleviate the typical "wearing off" effect after
> the optimum dosage of the medication has passed peak
> dose.
>      Glutamate is an amino acid which causes nerve cells in
> the brain to be more active.  PWP experience a decrease of
> dopamine in the brain which causes increased activity in the
> subthalamic nucleus.  The increase in neural activity in turn
> causes tremor, and stiffness.  Researchers believe that
> increased glutamate activity may be toxic to nerve cells.
>      Remacemide is considered a glutamate antagonist which
> will block the glutamate effect and thereby enhance the
> levodopa effect.
>      Patients chosen for the study must be sensitive enough
> to their condition that they can differentiate between an on or
> off period while on levodopa.
>     I will not be participating in any study.  Good luck.
>         Stephan 53/7
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 21:10:51 -0500
> From:    Camilla Flintermann <[log in to unmask]>
> Subject: Peter's neuro-clinic visit
>
> Friends--you may recall that we were going to see a "genuine movement
> disorder specialist" at the Aring Neurological Institute, U. of Cincinnati,
> having given up on our other neuro after the MIRAPEX debacle.  The appt.
> was today, and went very well. We are to try REQUIP (Ropinerole) instead
> of Mirapex again, but at a very slow rate in titration--about 1/3 of the
> schedule recommended by the manufacturer.  Dr.Samaha mentioned that in
> older patients the introduction should go more slowly, while for younger
> ones the usual schedule works OK.  He also confirmed that Mirapex is known
> for having considerable degree of hallucinations. We are to work our way up in
> dosage gradually,checkimng with him if there are serious side effects, and
> return in 3 months.  Peter liked him, and I'm so glad we went,despite the long
> trip.  That clinic, BTW, started last year to do pallidotomies, using the
> "mapping" technique learned at Emory, I believe.
> So tomorrow we start REQUIP, and thanks to Ernie for sending us the info
> re: his experience with it, which was  encouraging. Dr. S. agreed that
> we should not expect any changes/improvement at the lower doses, just as
> Ernie said.
> BTW, they are printing in their neurology dept. (u. of Cincinnati)ews-
> letter an article I wrote re: the PD and CARE lists, so we may get some new mem
> bers!
>
> Camilla Flintermann, CG for Peter, 79/8, Oxford,Ohio
> [log in to unmask]
> *   *   *   *   *   *   *   *   *   *   *   *   *   *
> "Ask me about the CARE list for PD caregivers!"
> *   *   *   *   *   *   *   *   *   *   *   *   *   *
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 20:09:50 -0500
> From:    Carol Horner <[log in to unmask]>
> Subject: Photography tips/Photos of Phila.
>
> --WebTV-Mail-2096224377-4833
> Content-Type: TEXT/PLAIN; CHARSET=US-ASCII
> Content-Transfer-Encoding: 7BIT
>
> For those of you who might be interested in photography, you might like
> to look at the photographs at this Philadelphia newspaper site.  My
> neighbor is a photographer for the Philadelphia Inquirer and these were
> featured in the Sunday Magazine of the paper a few weeks back.
>
> There are thirteen photos and all but the last two or three are great.
> Hope someone enjoys them!
>
> Carol Horner
>
> --WebTV-Mail-2096224377-4833
> Content-Type: TEXT/PLAIN;
>         X-URL-TITLE="http://www.phillynews.com/packages/photog/index.html";
>         CHARSET=US-ASCII
> Content-Transfer-Encoding: 7BIT
>
> http://www.phillynews.com/packages/photog/index.html
>
> --WebTV-Mail-2096224377-4833--
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 21:39:08 -0500
> From:    KEn Becker <[log in to unmask]>
> Subject: Re: Please STOP filling the PD Digest with LENGTHY UNREADABLE CODE!!!
>
> Why don't we all just make 1500 copies of a self taken picture, and send one
> to every other person on this list? JUST KIDDING!!!!!!! Ken B
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 21:42:39 -0500
> From:    KEn Becker <[log in to unmask]>
> Subject: Re: Glossary &  Humor
>
> Don, those were pretty good stuff, here are some in return:
> "It is better to be strong, healthy and rich, than to be weak, sickly and
> poor."
> "Keep your chin up...........so you can kicked in the neck!"
> "It was a terrible tragedy, but it could have been much worse, it could have
> happened to me"
> Inspirational words by ME!
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 11:40:42 -0500
> From:    Stephan Schwartz <[log in to unmask]>
> Subject: Drug Trials -Reply
>
> 10/27/97
> Brian:
>      On 10/24 I posted the message below to the Parkinsn
> list, but I have not seen it . . . did you receive it?
>      Stephan 53/7
> On 10/24 Brian Collins wrote:
> >>>. . . Remacemide . . . drug trials in the U.S. . . . . anyone
> taking part in a trial?<<<
> Hi Brian:
>      One of the 10+ centers conducting a clinical trial of
> remacemide hydrocholride is The Columbia-Presbyterian
> Medical Center in NYC.  The study will last 6 weeks.
>      Researchers report that this medication inhibits the
> glutamine cells of the basel ganglia (the center of motor
> control of the brain).  Researchers are trying to determine if
> remacemide can alleviate the typical "wearing off" effect after
> the optimum dosage of the medication has passed peak
> dose.
>      Glutamate is an amino acid which causes nerve cells in
> the brain to be more active.  PWP experience a decrease of
> dopamine in the brain which causes increased activity in the
> subthalamic nucleus.  The increase in neural activity in turn
> causes tremor, and stiffness.  Researchers believe that
> increased glutamate activity may be toxic to nerve cells.
>      Remacemide is considered a glutamate antagonist which
> will block the glutamate effect and thereby enhance the
> levodopa effect.
>      Patients chosen for the study must be sensitive enough
> to their condition that they can differentiate between an on or
> off period while on levodopa.
>     I will not be participating in any study.  Good luck.
>         Stephan 53/7
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 21:57:12 -0500
> From:    KEn Becker <[log in to unmask]>
> Subject: Re: Pictures,Pictures,Pictures!
>
> Liz, I got the message, no pictures, or files???? Did you send me the Barbie
> Doll
> jingle, if so we enjoyed it, if not it was other Liz, so never mind (grin)Ken
> B
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 11:43:38 -0500
> From:    Stephan Schwartz <[log in to unmask]>
> Subject: Selegiline -Reply
>
> Brian:
>     On 10/24/97 I posted this note to the Parkinsn list, but I
> have not seen it.  Did you receive this message?
> >>>Hello Brian:
> >>> Brian Collins <[log in to unmask]> 10/23/97
> 07:43pm >>> wrote:
> >>>OK, I give in. I promise not to write against selegiline
> ever again (Well, not this week anyway).  I had hoped to have
> a friendly debate about Selegiline: Dennis had volunteered to
> referee, and he seemed to be fairly impartial (- At least, he
> seemed to have an equal number of chips on each shoulder)
> But it all got too personal<<<
>
>      Hey Brian, I'll play!  I believe the subject is "Why take
> Eldepryl (Selegiline)?"
>     Any special rules?  Dennis Greene need not absent
> himself from the multilogue . . . I'm certain you'll conduct
> yourself like the Peer you are.  Okay, here goes:
>      Eldepryl is considered to be a selective MAO-B inhibitor
> prescribed by some neurologists to prolong the effectiveness
> of levodopa and reduce motor fluctuations and by other
> neurologists in an additional attempt to slow the
> degeneration of brain cells.  I have not read anywhere that it
> is touted as a "cure" for PD.  But, neither is levodopa.
>      Dr. Duvoisin, M.D., in his book "Parkinson's Disease,"
> 2nd ed. states that adding Eldepryl to the meds is the
> equivalent of increasing levodopa by about 20%.
>      Several recent studies (some of which were posted on
> this list by Janet Paterson) have concluded that therapy with
> Selegiline offers beneficial, long-term effects on the
> progression of PD.
>      However, researchers have not been able to isolate the
> mechanism that is at work.  It can be neuroprotective,
> symptomatic or even restorative.  Most neurologists believe
> that they can only perceive a symptomatic effect, with little
> evidence to support the theory that it is neuroprotective.
> Notwithstanding, Eldepryl has an important symptomatic
> (improvement in motor fluctuations) and levodopa sparing role
> in the treatment of PD.
>      The effects of Eldepryl upon the parts of a human nerve
> cell that are susceptible to premature death are being
> studied. Dr. Gerald Cohen, at the Mount Sinai Medical
> Center in NYC, is studying the connection between the mao
> enzyme and damage to a cell's mitrochondia (energy plant)
> and PD.  He is trying to determine if desmethylselegiline ( a
> result of the breakdown of selegeline) has a neuroprotective
> effect on the nerve cell.
>      So, what's the rumpus?   When I first sought treatment
> for PD (7 years ago this Christmas Eve, oops! wrong story)
> my neurologist prescribed Inderal ( a beta blocker) which
> reduced my tremor considerably for 12  months.  Then as PD
> progressed and I lost the symptomatic effect of the Inderal,
> he prescribed Eldepryl.  Again, the tremors were reduced
> and my gait improved for about 12  months when I began
> Sinemet.  Its been Sinemet and Eldepryl for the past 5 years
> and I have not experienced an increase in my PD symptoms.
>      My time's up - your turn.
> Stephan 53/7
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 22:07:26 -0500
> From:    Nancy Vanhook <[log in to unmask]>
> Subject: Introduction
>
> I am new to the list and have been lurking for a while here in snowy Iowa
> where it was 15 degrees this morning--breaking a record set in 1942.  Thanks,
> Colorado, for sending the snow our way.  Next time you may keep it.  It is
> only October!
>
> It has been fun getting to know all of you and seeing how supportive you are
> of each other.  Your humor is also enjoyed.   I am 54/5 and have drifted
> along with my parkinson rather slowly, I believe, considering  that I've had
> three moves (one to Germany), gone through empty nest, lost my dog and two
> birds, and done lots of travel during the last five years.
>
> I started on Eldepryl right away and had lots of trouble adjusting to it.  I
> went down to a half pill twice a day and slowly worked  up to two pills a
> day.  After two years I started on Madopar and switched to Sinemet in the
> states.  I now take two 5 mg of Eldepryl  and two Sinemet CR 25/100 per day.
>  But, it doesn't seem to be enough.  I need something more for cramps/curling
>  in my toes.  (Hard to putt when that happens.)  Also my right hand is very
> stiff.  My arm gets very jumpy at movies.  I'm not sure if it the excitement
> of the show or Brad Pitt.  I usually have to sit on my hand.
>
> I have a good movement disorder doctor, but would like some ideas of what to
> ask for.  I have tried increasing my Sinemet by 1/2 pill, but that doesn't
> help.  I would welcome any suggestions, commets, jokes or support.
>
> Nancy Van Hook   ([log in to unmask])
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 22:51:48 -0500
> From:    Arlene Walsh <[log in to unmask]>
> Subject: Re: Mirapex or not
>
> Hi, Marcia,
> Jim 63/14 has been on Mirapex for 8 weeks now.  Due to some hallucination
> problems I started his therapy MUCH slower than the norm.  I increased the
> dosage MUCH slower than suggested  i. e. 0.125mg every 3 days.  I flet that
> any adverse reaction wuld not be so severe and I could back away much
> quicker.  I work all day, so I could not have Jim having a bad day and my not
> be here.  Jim is up to 3.0 mg per day.  His drooling is verturlly gone, his
> off times are very much fewer, his cognitive skills  not much better, and
> speech is no better.  But his overall abilities are better including his
> sleep.  God willing we will continue.  Hope this helps.
> Arlene CG
>
> ------------------------------
>
> Date:    Fri, 24 Oct 1997 16:25:24 -0400
> From:    Stephan Schwartz <[log in to unmask]>
> Subject: Selegiline -Reply
>
> Hello Brian:
> >>> Brian Collins <[log in to unmask]> 10/23/97
> 07:43pm >>> wrote:
> >>>OK, I give in. I promise not to write against selegiline
> ever again (Well, not this week anyway).  I had hoped to have
> a friendly debate about Selegiline: Dennis had volunteered to
> referee, and he seemed to be fairly impartial (- At least, he
> seemed to have an equal number of chips on each shoulder)
> But it all got too personal<<<
>
>      Hey Brian, I'll play!  I believe the subject is "Why take
> Eldepryl (Selegiline)?"
>     Any special rules?  Dennis Greene need not absent
> himself from the multilogue . . . I'm certain you'll conduct
> yourself like the Peer you are.  Okay, here goes:
>      Eldepryl is considered to be a selective MAO-B inhibitor
> prescribed by some neurologists to prolong the effectiveness
> of levodopa and reduce motor fluctuations and by other
> neurologists in an additional attempt to slow the
> degeneration of brain cells.  I have not read anywhere that it
> is touted as a "cure" for PD.  But, neither is levodopa.
>      Dr. Duvoisin, M.D., in his book "Parkinson's Disease,"
> 2nd ed. states that adding Eldepryl to the meds is the
> equivalent of increasing levodopa by about 20%.
>      Several recent studies (some of which were posted on
> this list by Janet Paterson) have concluded that therapy with
> Selegiline offers beneficial, long-term effects on the
> progression of PD.
>      However, researchers have not been able to isolate the
> mechanism that is at work.  It can be neuroprotective,
> symptomatic or even restorative.  Most neurologists believe
> that they can only perceive a symptomatic effect, with little
> evidence to support the theory that it is neuroprotective.
> Notwithstanding, Eldepryl has an important symptomatic
> (improvement in motor fluctuations) and levodopa sparing role
> in the treatment of PD.
>      The effects of Eldepryl upon the parts of a human nerve
> cell that are susceptible to premature death are being
> studied. Dr. Gerald Cohen, at the Mount Sinai Medical
> Center in NYC, is studying the connection between the mao
> enzyme and damage to a cell's mitrochondia (energy plant)
> and PD.  He is trying to determine if desmethylselegiline ( a
> result of the breakdown of selegeline) has a neuroprotective
> effect on the nerve cell.
>      So, what's the rumpus?   When I first sought treatment
> for PD (7 years ago this Christmas Eve, oops! wrong story)
> my neurologist prescribed Inderal ( a beta blocker) which
> reduced my tremor considerably for 12  months.  Then as PD
> progressed and I lost the symptomatic effect of the Inderal,
> he prescribed Eldepryl.  Again, the tremors were reduced
> and my gait improved for about 12  months when I began
> Sinemet.  Its been Sinemet and Eldepryl for the past 5 years
> and I have not experienced an increase in my PD symptoms.
>      My time's up - your turn.
> Stephan 53/7
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 23:12:02 -0500
> From:    Arlene Walsh <[log in to unmask]>
> Subject: Re: Possible Mirapex Problem?
>
> Barb,
> Jim has MUCHO hip problems from the start so It is hard to day if it is
> Parkie related.
> We just went thru a short course of cortisone - nothing elso helped and some
> stuff actually aggravated the freezing problem (weird isn't it).  But the
> nausea is something we can talk about.  I have Jim take some Lysine (500mg)
> with each dose.  It did seem to with relieving nausea  and stomach burning
> from the strong arthritis medicatin, so I thought it might help as well with
> Mirapex.  We haven't had the nausea so far  (1.0 mg. 3xper day Mirapex).  But
> this could be like Lysine keeping away pink elephants.....we haven't seen any
> of them either!
> Arlene CG Jim63/14
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 18:12:11 -0500
> From:    jim and emily jackson <[log in to unmask]>
> Subject: seligiline-reply
>
> I vote to continue the seligiline debate--we personally are at a critical
> juncture re choices for treatment, and appreciate the input.
>
> Brian: what about taking seligiline at relatively low doses vs. high doses
> vs. not at all?  Jim has upped his seligiline from one to two 5mg tabs
> daily, says he thinks it is helping him symptomatically (tremors and
> fatigue).  No problems with dreams or insomnia.  I have seen and heard so
> much about the limited-term(5-year) efficacy of sinemet that I tend to
> agree with our neuro about waiting to start it, especially as he has a lot
> of trouble adjusting to new meds.  Jim really isn't too badly off, this
> early in the disease.  So naturally the purported neuroprotective aspects
> of seligiline are VERY interesting to us.  The info in your most recent
> post surely has made the decision difficult, though:
>
> >a neurologist who is close to, but not a member of the people who reported
> >the story, recently told me that in his view, the various critcisms made
> >about the methods used etc, were valid, but if the data are corrected for
> >these errors,  they affect but do not eliminate the basic scary story....
> >I have also heard from two people who tried to give up Selegiline, and
> >found that they couldn't.- Whether psychological or physical dependency
> >was to blame I could not say, but there must be a risk of some people
> >becoming hooked on it.
> >   New data which I first heard about while reading the transcript of an
> >interview with Professor Olanow makes it clear that the long-term condition
> >of people taking Selegiline, compared with a control group showed that the
> >early advantage (which was clearly present in the early years) apparently
> >evaporates over a 5 to 10 year period.
>
> So let's keep talking about seligiline.  Our original neuro has just moved;
> I am saving this discussion to present to his replacement when we see her
> next month.   Her reactions should give us a pretty good indication of
> whether we will be able to work with her (and she with us?).
>
> Emily Jackson, CG Jim, 69/1+
> Emily Jackson
> [log in to unmask]
>
> ------------------------------
>
> Date:    Mon, 27 Oct 1997 23:35:14 -0500
> From:    Elizabeth Southwood <[log in to unmask]>
> Subject: PHOTO
>
> --PART.BOUNDARY.0.115.mrin46.mail.aol.com.878013312
> Content-ID: <[log in to unmask]>
> Content-type: text/plain
>
> GIF photo taken this summer - Liz
>
> --PART.BOUNDARY.0.115.mrin46.mail.aol.com.878013312
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> n+/wD5q6vAAMAAzAAAwADv7/8A/est - 27 Oct 1997 - Special issue
> ****************************************************
Please stop sending pictures. We read PD Digest daily and learn much
from what other people share, but it takes up a ton of memory to do
pictures and forever to open the document, and some of us do not have
the capability to convert the code to a photo, so we don't get to see
the pictures either. Thanks for your consideration.