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		LISTSERV Archives
		PARKINSN Home
		PARKINSN April 1998, Week 3

Subject:

Re: Cell transplants

From:

Joao Paulo Carvalho <[log in to unmask]>

Reply-To:

Parkinson's Information Exchange <[log in to unmask]>

Date:

Wed, 15 Apr 1998 11:50:03 -0300

Content-Type:

text/plain

Parts/Attachments:

text/plain (127 lines)

Dear Barbara,

You are quite rigth that my statement is not 100 % correct.
Perhaps what I should say, being more precise, is that pallidotomy does not avoid
the continous progress of PD in years later.In other words, it is not a cure of
PD. Is that true ? I would like it were not. Thanks God it brings blessed relief
for many important symptoms.

The question arised is : would cell transplant avoid futher future progress of PD
? and then,there would have gains in have it associated with other surgeries in
some cases ?

Cheers,

Barbara Mallut wrote:

> A quick comment, Joao Paulo, regarding your statement that pallidotomy loses
> it's effectiveness in a few years.... That is generally thought to be
> incorrect by the medical community, I believe... at least according to Dr.
> Robert Iacona, who to date has preformed more than 1000 pallidotomies.
>
> Meanwhile, my unilateral pallidotomy - performed 4 1/2 years ago at Loma Linda
> Med. Center - continues to give me blessed relief from PD symptoms in my right
> side.  The LEFT side?  Well, that's another story (and maybe another
> pallidotomy eventually)
>
> I guess this is a case of "time will tell," whether or not the benefits from
> the surgery continue on indefinitely tho, huh?
>
> Barb Mallut
> [log in to unmask]
>
> ----------
> From:   Parkinson's Information Exchange on behalf of Joao Paulo Carvalho
> Sent:   Tuesday, April 14, 1998 12:56 PM
> To:     Multiple recipients of list PARKINSN
> Subject:        Cell transplants
>
> --------------4BF8ADA72A53FF1F40BFBFD6
> Content-Type: text/plain; charset=us-ascii
> Content-Transfer-Encoding: 7bit
>
> I quote :
>
> > Schumacher will report on a study of pig cell transplants later this
> > month at the annual meeting of the American Association of Neurological
> > Surgeons. The study was designed to look at the procedure's safety
> > rather
> > than effectiveness, and Schumacher said no major side effects appeared.
> >
> > Most of the recipients improved to some degree, he said. As a group,
> > the 11 patients improved about 14 percent on standard rating scales by
> > six months after surgery and about 20 percent by a year afterward,
> > Schumacher said. One other patient died from a cause unrelated to the
> > treatment.
> >
> > "The patients continually improve," he said. "They're not made
> > immediately
> > better, but they improve over time as the graft matures."
> >
>
> Considering the small improvement (15 to 20 % ) of this risky surgery I
> would like to ask to the specialists if it would'nt be a good ideia to
> associate it (perhaps at the same time or not) with a Pallidotomy or
> else a Talloctomy ?
>
> It is known that the improvement with Pallidotomy is noticeable and
> occurs in few weeks,or rather immediatly but looses effectivness with
> years ahead. On the other way, the cell transplants seems to improve the
> symptoms only after long periods of time.The ideia being that the
> association of both surgeries would add the gains of each one for
> better.
> --
>    +----| Joao Paulo de Carvalho   |------ +
>    |         [log in to unmask]     |
>    +--------| Salvador-Bahia-Brazil |------+
>
> --------------4BF8ADA72A53FF1F40BFBFD6
> Content-Type: text/html; charset=us-ascii
> Content-Transfer-Encoding: 7bit
>
> <HTML>
> I quote :
> <BLOCKQUOTE TYPE=CITE>
> <PRE>Schumacher will report on a study of pig cell transplants later this
> month at the annual meeting of the American Association of Neurological
> Surgeons. The study was designed to look at the procedure's safety
> rather
> than effectiveness, and Schumacher said no major side effects appeared.
>
> Most of the recipients improved to some degree, he said. As a group,
> the 11 patients improved about 14 percent on standard rating scales by
> six months after surgery and about 20 percent by a year afterward,
> Schumacher said. One other patient died from a cause unrelated to the
> treatment.
>
> "The patients continually improve," he said. "They're not made
> immediately
> better, but they improve over time as the graft matures."</PRE>
> </BLOCKQUOTE>
> &nbsp;
> <BR>Considering the small improvement (15 to 20 % ) of this risky surgery
> I would like to ask to the specialists if it would'nt be a good ideia to
> associate it (perhaps at the same time or not) with a Pallidotomy or else
> a Talloctomy ?
>
> <P>It is known that the improvement with Pallidotomy is noticeable and
> occurs in few weeks,or rather immediatly but looses effectivness with years
> ahead. On the other way, the cell transplants seems to improve the symptoms
> only after long periods of time.The ideia being that the association of
> both surgeries would add the gains of each one for better.
> <BR>--
> <BR>&nbsp;&nbsp; +----| Joao Paulo de Carvalho&nbsp;&nbsp; |------ +
> <BR>&nbsp;&nbsp; |&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
> [log in to unmask]&nbsp;&nbsp;&nbsp;&nbsp;
> |
> <BR>&nbsp;&nbsp; +--------| Salvador-Bahia-Brazil |------+
> <BR>&nbsp;</HTML>
>
> --------------4BF8ADA72A53FF1F40BFBFD6--



--
   +----| Joao Paulo de Carvalho   |------ +
   |         [log in to unmask]     |
   +--------| Salvador-Bahia-Brazil |------+

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