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> From: Sharon & Jim LeBlanc <[log in to unmask]>
> To: [log in to unmask]
> Subject: References for Theory of Environmental Parkinsons - Pollutant
Botulism - Clostridium Botulinum
> Date: Monday, July 05, 1999 12:36 PM
>
> 1.Boston Globe - June 27, 1999 - Pretty Poison by Saltus - first the
> eyelids droop, then the muscles for speaking grind to a halt, then
> swallowing and breathing muscles go dead. (Article on BOTOX injections
and
> use in Parkinsons dystonia)
> 2.Retinoic Acid induces abnormal hindbrain and craniofacial development
in
> Macaque - by Andrew Hendreckx - CRISP
>   13-cis retinoic acid - cRA, isotrentinoin,Accutane
> 3.Neuro-opthalamogic manifestations of Parkinsons Disease - by Jacqueline
> Winterkorn - Color vision in the blue/yellow axid seems particularly
> affected. (colorblindness).
> 4.Olfactory dysfuntion in Parkinsons - PMID 9153598 - unusual pattern of
> selective loss to certain odours - (Birth defect).
> 5.New test may identify genetic risk for Parkinsons - Dr. Erwin
Montgomery
> - Tests of motor function, smell, and mood.
> 6. Spectrum Laboratories search for cRA chemicals, (includes about 100)
> N-nitrosodimethylamine and dimethylamine which becomes
> N-nitrosodimethylamine in air. Dimethyamine - Pesticide propellant,
> gasoline stabilizer, accelerator in vulcanized rubber, textile chemicals.
> Formation of carcinogenic nitrosamines can occur in the stomach when
> secondary amines, such as those present in fish, vegetables, and fruit
> juices come in contact with nitrite, which is often used as a food
additive
> in meats and smoked fish. Excreted in urine. Inhibited transglutaminase
> activity (Huntingtin - binds with AAT which binds with CCAAT) and glucose
> stimulated insulin release.Leaches into the soil. (Farmers - Nitrogen
> fertilizers). Found in tobacco. Released in wastewater during its
> production and use.The ability of amines to form complexes with metallic
> ionw is well known. Metallic ions in the soil and natural waters may
> therefore combine with dimethylamine.Identified in uncultivated soil in
> Moscow. Found in many fresh foods and fish. Found in cattle manure and
> bacon and cook-out food and food packaging. Released from plastics used
in
> building materials.  N-nitrosodimethylamine is an industrial solvent,
> nematocide, used for inhibition of nitrification in soil, plasticizer,
> high-energy batteries. May be released in the environment as a solvent
> rubber accelerator. Found in wastewater effluents, diesel and gasoline
> exhaust, released in the air by industries including foundry, rubber,
> chemical, dye, leather, fish processing, and surfactant operations.
Highly
> mobile and will leach extensively. Has been found in cheese, milk, bacon,
> edible oils, bisquits, dried peas, vinegar, margarine, infant formula,
> fish, tap water, smoke-filled rooms of cigarette smoke , in the ambient
air
> of several large cieits and at a number of industries.
> 7.Functional food science and gastrointestinal physiology and function -
S.
> Salminen - University of Ulster, Coleraine UK - Intestinal microflora
that
> inhibit the gut - Clostridium - Fermentation of short-chain fatty acids
> includes dimethylbutrate, producing amines. Other gut bacterial products
> include N-nitroso compounds, which are formed by bacterial catalysis of
the
> reaction of nitrite and nitrogenous compounds in the colon. (N- nitroso)
> (dimethyl) (amine) . Butyrate leads to increased tumor formation.
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