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Hi everyone, Has anyone ever taken Zanaflex for muscle ridigity? I am in the early stages of PD and have been on Mirapex 4.5mg per day. The Mirapex is not really helping and my neuro wants to take me off, today and tomorrow I am decreasing to 3mg then on Friday I am to take only 1.5mg and call him to begin Zanaflex. I am a little reluctant to give up on the agonists because of what I hear they can offer some nerve protection. Does anyone else take only Zanaflex? Isn't that just a muscle relaxer? What about other symptoms, can it help control them? I would like to be as informed as I can be when the nurse calls so I can ask the right questions. I must admit to a person who has never been sick, this whole thing of dealing with doctors and insurance is really an experience in itself! I am still thinking of the time when you called the doctor you actually talked to the doctor not the nurse. Now I love my nurse, but having to ask him questions through her somehow loses something in the translation! But I am getting better thanks to this group, I have caught her off guard at times when I ask about meds by name etc. Thanks in advance for all of your experienced opinions, that is what is so great about this group. Sherry 49/48/43