Hello Brian, Happy New Year from Denmark. ----- Original Message ----- From: Brian Collins <[log in to unmask]>>> **********I feel very lucky because I was treated with Sinemet CR from that day 6 years ago I got my diagnosis. The last 3 years I have been able to stay on 700 mg Sinemet CR a day and like you I also take Pergolide - only 0,75 mg a day because I suffer much from nausea if I take more. My PD increase very slow now and I`m getting used to live with it. Of course I`ll like to feel better so I tried Tasmar and Comtes but became very ill from the sideeffects. Now Ì have taken Pramipexol for 3 month and it gives me more energy and no sideeffect. (called Sifrol in Denmark) BUT I agree with you about Sinemet, and in my opinion let people start treatment from the first day they are diagnosed instead of suffering unnecessary. Hope you are doing well. Sonia Nielsen Denmark NEVER GIVE UP Sent: 31. december 1999 01:21 Subject: Re: Lets hear it for Sinemet > Hello friends I wrote the following e-mail to this group about three weeks > ago, and was disappointed to see it only produced 3 answers. Surely this > fundamental question should be exposed? After all, we know from their previous > letters that many of our contributors are on the receiving To: <[log in to unmask] of one or other > of these strategies - I can't believe that they are content to be led off on > a path to potential damage. Here is the story one more time- > > On Fri 17 Dec, Brian Collins wrote: > . I won't go to the lengths > of quoting all the detailed articles here; suffice it to say that a long > and bitter debate is raging amongst the upper echelons of the neurologist > fraternity, about whether moving away from Sinemet, or avoiding Sinemet for > as long as possible is good or bad for you. Make no mistake - they can't > both be right, and those who are in the wrong camp (The abandon Sinemet > camp if you are not sure where I am coming from) are grimly leading their > patients deeper into the quicksands every day. > I have already made my Sinemet go > continuously for 20 years- it's easy, anyone can do it, all it takes is a > little common sense. My writing on this subject is available to all, so I > will say no more. What else? Well, I have made the Sinemet go even further, > when it became impossible to use alone at 14 years, and six years on, I have>to take 6 mg of Pergolide to balance the Sinemet, and I'm doing well, but > I am sailing very close to the wind, and the message is: You cannot afford > to play fast and loose with Dopamine agonists. They are, in my view, a lot > more dangerous than Sinemet in their potential side-effects, and must be > treated witth respect. There is a proper place for them, and I think it is > later rather than earlier. > One last warning; The New Agonists cost a LOT more than Sinemet don't > they? When you get your next bit of advice (or read about how great Re-Quip > , Mirapex, etc, etc is) just ask yourself who is paying their wages! > -- > Brian Collins <[log in to unmask]> (59/39/34) > > -- > Brian Collins <[log in to unmask]> (59/39/34)