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Sounds to me like you were being brought on meds too fast. Everyone is different. I was recently put on a pain killer, normal dose 1to 2 tablets every 4 hours, before and after surgery. One/half of a pill was the most I could tolerate --- most of the time I took 1/4 of a pill at a time and took a second 1/4 pill 2 hours later. I am a small person. At the prescribed rate I passed out and they had to call 911. They tried a different med in the hospital. I only agreed to take 1/2 of the dose. I don't think I touched the sheets for the next 2 hours. I felt like I was floating. Paul ISTSERV.UTORONTO.CA> Sent: Friday, January 07, 2000 6:55 PM Subject: Mirtazapine You may remember that I was going to try Mirtazapine for my tremor. My neurologist had me start slow (1 pill/night for the first three or four nights, then call him to determine what to do next - three pills/day is the normal dose). I started Wednesday night, took one pill and woke up fifteen hours later. No tremor during that period, but there never is a tremor while I sleep. I got up at noon yesterday and felt very tired. It took a couple more hours to wear off - then I was back to normal. It was such a knock out I couldn't put myself through it again. So, I'm back to a constant shaking, but I have some energy again. At the same time I don't want to discourage anyone from trying it. Very few meds work for me the way they are supposed to. Joan 58/48