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Mama tried Comtan back in November. After only 4 days of titrating upwards she experienced physical weakness, balance problems and major dyskenisia/dystonia of the head and neck. I believe she tapered off but having only been on it for four days the tapering may not have made a difference. The bad side effects went away after stopping the Comtan. Teresa, Daughter of Mama (57/43/38) -----Original Message----- From: Parkinson's Information Exchange Network [mailto:[log in to unmask]]On Behalf Of First & Last-Name Sent: Monday, January 10, 2000 3:00 PM To: [log in to unmask] Subject: Comtan discontinued ------i'm feeling worse each day on contam (6/day + 6 sinemet). now in addition to depression, constipation, sleeping, 'i'm tasting the med and feel dizzy and have ringing in my ears. this a.m. neurol said stop contam and take sinemet every 3 hrs day and night (he said 7, but that means 8). i specifically asked about tapering contam but he said additional sinemet would cover it. i want to do as he suggests, want to get off contam but package insert does say taper. any experience, ideas, suggestions? thank you nancy spires