Has anyone on the List heard of SAM-e to be used for depression? My understanding is that SAM-e is a "nutritional supplement" which has been used quite successfully in Europe for many years. I am currently taking Sinemet and Tasmar for PD and was wondering if anyone has heard of any negative interactions between between SAM-e and Sinemet and/or Tasmar. Many thanks. Joseph Konick Age 47 - diagnosed 10 years