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we newcomers are glad to hear your views/experience. i've had trouble dealing with agonists (eldepryl, mirapex, comtan) and am again on "sin" only. i have trouble convincing my family that fewer meds are better for me if i am not in a fog. ones who are not pd-ers say oh aren't the new drugs/surgeries wonderful? i prefer to be less mobile and more alert, but sometimes i feel alone when i say new drug is poison for me. thanx for encouragement. nancy.