Hi First & Last-Name I to have a hard time taking agonists, but I am able to take Requip .25 mg three times a day along with the Sinemet 25/100 CR two times a day. How every though I was not able to take larger doses of the Requip I was at 1 mg three times a day and it made me very sick, lost weight and such sick to my tummy. The lower dose is working fine for me. I also do not like taking a lot of meds, I do take a lot of vitamins and herbs. Janice 52/50/46 ----- Original Message ----- From: First & Last-Name <[log in to unmask]> To: <[log in to unmask]> Sent: Monday, January 17, 2000 12:46 PM Subject: bcollins+sin > we newcomers are glad to hear your views/experience. i've had trouble dealing > with agonists (eldepryl, mirapex, comtan) and am again on "sin" only. i have > trouble convincing my family that fewer meds are better for me if i am not > in a fog. ones who are not pd-ers say oh aren't the new drugs/surgeries > wonderful? i prefer to be less mobile and more alert, but sometimes i feel > alone when i say new drug is poison for me. thanx for encouragement. nancy. >