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Ervin, I have been in the same situatuation, I decided to bring the 25/100 to the Pharmacy and let them destroy them, because I felt more safe taking 50/200 CR. Maybe it seams a little stupid :-)) but menthally I felt better taking the right prescription. Sonia N ----- Original Message ----- From: Ervin McCarthy To: [log in to unmask] Sent: 22. januar 2000 17:43 Subject: Sinemet A question about Sinemet. The doctor gave me a prescription for 50/200CR four times a day. If I use up the remainder of my Sinemet 25/100CR two pills to equal the 50/200 C. R will that have the same effect? it may seem like a dumb question but I have a lot of 25/100CR left. Thanks for any information.