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Bob, My non-professional, non-medical, advice. Not even advice, just a suggestion. You need more sinemet. I also had good results with permax at one time and only changed to requip for the sake of change. Greg 47/35/35 BOB WROTE: Subject: Mirapex, Requip, Comtran Advice neded > I need some advice from anyone who may have had similar experience with > the following: > I was taking Mirapex (1.5 mg per day) titrated from .375 mg per day over > 8-9 months. I developed swollen ankles and "sleep attacks" the next 2-3 > months. I tried relafin for swollen ankle, didn't work. Dr. then put > ankle in a cast for a month, that didn't work either. I read on the list > where some were having similar problems be cause of Mirapex. I stopped > Mirapex (slowly) and swollen ankles and sleep attacks were gone, 4-5 > months ago. Neuro thinks I am now under medicated because of increased > tremors, slower gait, minor balance problems and increased drooling. He > says I have two options, add requip to meds or add straight Sinemet and > increase Sinemet CR ( I now take 21/2 tabs per day, 50/200 Sinemet CR) > That's my only sinemet med > I am afraid Requip will have the same side effect of swollen ankles and > "Sleep Attacks" as Mirapex did. > What would you do? > Bob Chapman 66/60/55 >