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Sandi, I truly thank you for your suggestion and for taking the time to respond to my post. I had wondered about some of the personal information I had read concerning some antidepressants since I joined the list. This was the first antidepressant I was given and it has worked very well for me over the past 10 years. I see a board certified psychiatrist and is also a board certified neurologist who prescribed it after first trying three months of twice weekly counseling sessions . I take the lowest doseage and have had no side effects from the outset. How I see life now is mostly positive. For anyone who has battled this kind of depression it is as night and day to come out the other side of it. I can not speak for how I would feel if it brought on pd, but I can speak for what it is to know that one small pill has made my life liveable. Now when someone says isnt it a wonderful day? I know what that means and feels like; that even if it is the worst possible day it is a good day.. for me. *seattle* audrey friend of aussie john pwp 48/40/38?? My last addition is to wish with all my heart that there will soon be an end to all of the suffering and pain, isolation and lonliness that is part of all of you connected with pd ... where is my fairy god mother now? --- From: BERNARD LEVENTHAL To: [log in to unmask] Sent: Monday, February 14, 2000 3:31 PM Subject: Re: dopamine ----- Original Message ----- From: Audrey To: [log in to unmask] Sent: Sunday, February 13, 2000 9:21 AM Subject: dopamine Hi list .. A thought struck me after rereading janet marie's comments. Is it a lack of dopamine in PD or is it the inability to manufacture and distribute dopamine in the brain? This is a dumb question probably, and another reason to keep my mouth shut most likely. If it is the lack of dopamine, does it help to use antidepressants (as prozac) to help counteract dopamine loss? I ask because this is the medication I take each day for clinical depression. As I read further about pd, I keep seeing references to restless leg syndrome. This is caused by the lack of dopamine also I believe, and I have had this syndrome as long as I can remember..Why then isn't the family of in helping Dear Audrey. I am a lurker, but I read your letter and thought I had to reply, a few years ago I complained to my G.P. of being tired. I was concerned because my mother slept so much. He reccommended Prozac.After 6 wks and no improvement I said I wasstopping. He said I should try a different drug...Wellbutrin. I took ita day and felt better.suggested I up the dose ( against my better judgement) and I became violently ill.I developed a tremor (the beginning of my pd) lost my balance etc..The neurologist said that the drug did not cause the pd but brought it on early. Were all different, but if you don't need it or can live without it don't take it.Sandi