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----- Original Message ----- From: janet marie paterson <[log in to unmask]> To: <[log in to unmask]> Sent: Wednesday, February 16, 2000 5:32 AM Subject: PMID: 10672236: Glucose metabolism and neuronal degeneration in PD & AD Synaptic degeneration and death of nerve cells are defining features of Alzheimer's disease (AD) and Parkinson's disease (PD), the two most prevalent age-related neurodegenerative disorders. ----- Original Message ----- Can PD truly be defined any longer as an "age-related" disorder? That implies that onset begins at a certain, usually advanced age. Today the range falls somewhere between 20 and 80 years of age with the average continuing to decline. With the increasing prevalence of YOPD down to the late teens and early 20s --- "age-related" no longer seems to apply (unless that means any time after birth). What are your opinions? Paul