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Hi Chris - I was diagnosed 7 years ago and have an occasional glass of wine or two and it doesn't seem to be a problem at all. Never really asked the doctor about it (I guess I figured what I didn't know wouldn't hurt me!) Have noticed that more than two glasses can definitely make a difference but I guess that's true for just about everyone! Hope this helps. Debby H. 46/diag. 7/ symp. 12