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To Mary McNeely Mary, I have been taking Permax since 1989 - I took part in the clinical trials. The only other medication I take is sinemet CR I've had PD since 1981. I take .625 mg of Pernax and one Sinemet CR 200/50 on waking - about 5:30 or 6 am and every 4.5 hours thereafter until I've had four doses. I must be lucky, but I've had no adverse effects from either drug in the ten years I have been on them. Dr. Tony Lang, my neurologist for 16 years, and a fabulous one, hasn't tried me on any of the new pd drugs becausethere have been no studied of any of them vis a vis permax - a great drug Cheers, Bill ----- Oriinal Message ----- From: "Phil E.Gesotti" <[log in to unmask]> To: <[log in to unmask]> Sent: Friday, February 25, 2000 4:46 PM Subject: Re: Permax and Side Effects > Marie McNeely wrote: > "Phil; can you please tell me what side effects you seem to be getting > from > Permax." > > Primarily I experienced stomach discomfort. This ranged from hunger > pains and craving sweets to heartburn and nausea. I had noticed > hyper-yawning attacks over the last year, but did not associate it with > the Permax. This hasn't happened since I quit taking it. What really > drove me to try cutting back was increased occurences of nausea. Then I > noticed that I wasn't getting unbearably sleepy in the afternoon. > > This is just my experience and should not be taken as an endorsement to > quit taking the drug. Many people take the drug without side effects and > it does have benefits. Maybe it's just us stubborn people that can't > tolerate the drug. Maybe they should do a study on mules to see if it > makes them sleepy. :-) > > Phil Gesotti 50/46+ >