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My mom has these cramps also, that force her to have to stand up for periods of time. They come when she is sitting - mostly late afternoons and evenings - and also during the night when she is sleeping - causing her to wake up and have to stand to relive them. In addition to PD+, she has been diagnosed with a pinched nerve in the 5th lumbar and nothing has worked to relieve these cramps and leg pains so far. We have tried cortisone shots and a series of epidurals - all to no avail. While seeing a foot doctor (for drop foot which occured while she was in the hospital in early 95) for unrelated reasons, she recommended us to see a certified pedorthist, thinking that possible modifications to shoes would help relieve the pressure, thus reducing the cramping. When the pedorthist saw my mom, she said modifications to the shoe wouldnt help relieve the pressure, but wants her to see a specialist (MD) in Physical Medicine & Rehabilitation (PM&R) at Oschner Medical Center in New Orleans (where we are). Apparently, this doctor is a specialist in muscle spasticity and the pedorthist thinks there may be something he can do in addition to attending a series of customized physical therapy workshops there. To make a long story short, we are going to see Dr. Kauffman at Oschner on March 23. If anything good comes of this effort, I will be glad to pass on any information at that time. David p.s.. Quinine water? Does this work at all? Never heard of using it as a medication for leg cramps. brad klainberg wrote: > anyone having chronic cramps in both legs, and any solution besides quinine > water ? > > gracias > bk > > ____________________________________________________________________ > Get your own FREE, personal Netscape WebMail account today at http://webmail.netscape.com.