 |
 |
Dr.Romero, Since you are an M.D. maybe you could give me an answer. The Neuro I have been going to gave me MYSOLINE 50mgs and I had to work my way up to 1 in the a.m. and 2in the p.m.What is this used for and why would my eyes feel swollen and sore around the eye lids? I have an appt. in Iowa City , Iowa on the 6th of April at a movement Disorder clinic. I still have the hand,jaw,tremors. Shirley ----------------------------------------------------- Click here for Free Video!! http://www.gohip.com/freevideo/ ----- Original Message ----- From: Jorge A. Romero, M.D. <[log in to unmask]> To: <[log in to unmask]> Sent: Tuesday, March 07, 2000 10:13 PM Subject: Re: amitriptyline > Amitriptyline is not contraindicated in Parkinson's Disease. > > Indeed, it can be beneficial in many ways: > > 1) it has anticholinergic activity which causes the side effect of dry > mouth. However this same anticholinergic activity may contribute to control > of tremor and bradykinesia. Remember the first antiparkinsonian drugs were > anticholinergic drugs (benztropine and trihexiphenidyl - Cogentin and > Artane, for example) > 2) it has mild pro-dopaminergic activity (it is a catecholamine reuptake > inhibitor) and thus could also by that mechanism exert a very mild > antiparkinsonian effect. > 3) it is a useful antidepressant - and 30 to 50% of PWPs are likely to have > significant symptoms of depression. > 4) it helps sleep - and many PWP have trouble sleeping. > > In selected PWPs, it can be a very useful drug. > > Jorge Romero, MD > > > ----- Original Message ----- > From: "Paul Lauer" <[log in to unmask]> > To: <[log in to unmask]> > Sent: Tuesday, March 07, 2000 5:44 PM > Subject: amitriptyline > > > > I have had a stiff neck now going on a year. Neither my neuro, my > orthopedist > > and now a physiatrist(sp?) think it is PD related and I think I that it is > > most likely arthritis. I won't bore you with the various things which have > > been attempted since that is not my current subject. Add to the neck > > problems, problems sleeping which are probably in some way PD related. As > a > > result of both problems, my physiatrist is prescribing amitriptyline, 10 > mg, > > which he says is a mild dose and should work both as a sleep aid and a > > painkiller. He further says that in larger doses it is an antidepressant, > > which I don't need. > > > > I found the drug in Kathryn Holden's drug database but it doesn't mention > one > > way or the other whether it is contraindicated for PD or not. Experiences > > anybody? > > > > Paul H. Lauer > >