Heard this on Sixty Second Housecall today and was particularly interested in the statement re 'generic drugs.' jmr 10 February 2000 You can't break tablets to save money ANCHOR LEAD: The increase in drug costs in the last ten years has been more than the average rate of inflation. It's lead many doctors to try and assist patients by prescribing larger than needed tablets, then having patients break them in half. But in today's Sixty Second Housecall, Dr. Bob Lanier reports breaking tablets in half could be dangerous... Viagra is expensive.... But ironically the twenty milligram tablet costs the SAME as the ten milligram - it doesn't take a rocket scientist to ask for the big tablet, then break it in half. ((** This sort of thing - breaking big tablets in half is sort of an underground secret of drug companies - some charge by the pill rather than the dose because the expense of the drug is not in the ingredients - it's the research and packaging. But can you break a tablet accurately and does that matter? A recent study asked about a hundred people to break tablets in half. The tablets were then weighed and compared. Almost half of the tablets had more than a ten percent size difference meaning that you get ten percent more on one dose and ten percent less on the next. May not sound like much.. but some medicines are dosed so carefully that it could make a difference. **)) and it's particularly a problem in ---generic drugs that already are allowed to fluctuate as much as ten percent from the real drugs.--- Breaking tablets? Reconsider For more information ask your doctor, or ask-dr-bob.com, I'm Dr. Bob Lanier. ANCHOR TAG: Breaking a drug in quarters, especially when it is not scored is a recipe for very inaccurate dosing. Surprisingly, most people in this study were willing to pay much higher prices for the not having to break tablets. REFERENCE: Modern Med vol67 no 5, 1999, Pharmocotherapy 1998:18:193 http://www.askdrbob.com/ -- Judith Richards, London, Ontario, Canada [log in to unmask] Today’s Research... Tomorrow’s Cure -- Judith Richards, London, Ontario, Canada [log in to unmask] Today’s Research... Tomorrow’s Cure