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On Fri 17 Mar, Nigel Harland wrote: > Hello Brian, > With regard to my dosage of Madopar, as well as the two > sizes of capsule you mentioned, they also come in a 62.5 mg size, so, taking > one 125 plus one 62.5, gives the 187.5. Since going down the Dispersible > route, these are only available in 125mg, however they are scored centrally, > so can be halved quite accurately, so one and a half of these again results > in 187.5(approx!) Incidentally, I did consult my neuro' before trying these > combinations and he okayed them, he is a chap who seems to know his stuff, > and understands that a certain amount of flexibility and fine tuning of > meds' may be necessary to get the best results. > Here's hoping all our gangplanks lead to the light at the end of the tunnel > !! > Regards > Nigel 45 diag' 12yrs > ----- Original Message ----- > From: Brian Collins <[log in to unmask]> > To: <[log in to unmask]> > Sent: Thursday, March 16, 2000 10:04 PM > Subject: Re: cabergolide > Hello Nigel I see - for some reason, I thought you were referring to a single tablet. I can set you right on one point however; there is most certainly a 62.5 Madopar Dispersible: It's white and round and a smaller version of the Madopar 125 dispersibl, complete with score marks. By the way, I have got a very good calibration of the Pergolide - I would be interested to see if anyone else has been able to get a handle on it. Over the past 6 years, I have held my Madopar intake constant at a nominal one and a half Madopar Dispersible every 2 hours - This gives me a constant 32.5 mg/hour of levodopa. (That is the base rate, I take more to navigate round meals- It works out to 800 mg per day. I am reaolved to keep the 800mg/day because I have noted occasional references to a lot of small side-issues which come creeping from various parts of the brain, as the total supply dwindles to the lower levels. Does anyone have any thoughts on this? I got sidetracked then (sorry). To return to the Pergolide: I have found that my demand rate for Pergolide (to avoid dyskinesias) is +1 mg of Pergolide per year, at a constant flow rate of levodopa. I think that the makers of Cabergoline have outsmarted themselves with their obsession with its long halflife. By only prividing one tablet, they have taken away all the initiative from those of us with a little curiousity left Regards, -- Brian Collins <[log in to unmask]> (60/39/34)