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Interactions of Sleep and Parkinson's Disease. Sleep disruption represents an important, and clinically relevant facet of Parkinson's Disease [PD]. This review attempts to integrate the current knowledge regarding sleep alterations in PD by examining following: -the nature of sleep disturbance in PD, -the influence of antiparkinson medication on sleep parameters, -the interaction of psychological conditions such as depression and anxiety with sleep, and -possible beneficial aspects of sleep in PD. Special emphasis is placed on rapid eye movement sleep behavior disorder and the evidence of it heralding PD and related disorders. Semin Clin Neuropsychiatry 2000 Jan;5(1):20-32 Razmy A, Shapiro CM Sleep and Alertness Clinic, Toronto Western Hospital, Toronto, Ontario, Canada PMID: 10704535 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10704535&form=6&db=m&Dopt=b janet paterson 53 now / 41 dx / 37 onset a new voice: http://www.geocities.com/janet313/ 613 256 8340 PO Box 171 Almonte Ontario Canada K0A 1A0