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On Mon 20 Mar, Ervin McCarthy wrote: > Forgot to ask does Sinemet alleviate tremors? I have been told no by my > neurologist. > > ----- Original Message ----- > From: Roxanna Nakamura <[log in to unmask]> > To: <[log in to unmask]> > Sent: Thursday, March 16, 2000 1:25 PM > Subject: Levodopa toxicity a myth? > > > > I just came across these interesting new articles in the > > AMA's Archives of Neurology: > > > > "Is Levodopa toxic?" > > http://archneur.ama-assn.org/issues/current/full/ncn8639.html > > > > "Levodopa toxicity in Parkinson Disease: Reality or Myth?" > > http://archneur.ama-assn.org/issues/current/full/ncn8638.html > > > > "Levodopa toxicity" > > http://archneur.ama-assn.org/issues/current/full/ncn8640.html > > > > Despite the titles, these articles are encouraging. > > Apparently, research does *not* support the theory that > > levodopa hastens disease progression or cell death. On the > > contrary, levodopa extends life and decreases disability. > > The real "toxicity" concern, the authors say, is whether/how > > levodopa really is related to motor fluctuations and > > dyskinesia. > > > These articles are very useful, and slot neatly into my model of the brain / levodopa interaction. I intend to write to the authors of the above reports, to see if they are interested in my work. I have been disappointed at the difficulty that I have encountered when showing it to some of the more senior neurologists :- I think that we have a communication problem - They simply cannot think of the system in the way that I define it. It is not my problem, I now realise - When I show it to Engineers, they understand it - when I show it to PWPs, They understand it, but not neurologists it seems. The hunt continues to find the worlds first Engineering Neurologist. By the way, Of course Sinemet alleviates tremor! Why does your neuro think we all take so much if it? Regards, -- Brian Collins <[log in to unmask]> (59/39/34)