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Send reply to:          Parkinson's Information Exchange Network <[log in to unmask]>
From:                   Ivan M Suzman <[log in to unmask]>
Subject:                Alive or dead?? a PWP's Substantia Nigra - 4 more questions
To:                     [log in to unmask]
Date sent:              Tue, 21 Mar 2000 12:07:31 -0500

> 1) Are the various pigmentation states of the substantia
> nigra known through post-mortem study, primarily, or have there been
> studies where this brain tissue has been observed in
> persons who are alive? Do these tissues come from autopsy?
> From surgical theaters?

Autopsy


>
> 2)  Do surgeons see these mid brain tissues regularly?
> Rarely? Almost never?

Never in the live patient.  The area is inaccessible surgically.



>
> 3) In examinations after death, would the
> color of the substantia nigra be different from what it was during life?
>    If different, could this difference be accounted for  either
> by the deposit of pigment(s), or by the precipitation of protein?
>

I don't know.



Best,

Bob


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