Does anyone have any comments on Sinemet 25/250? Is it considered a high dosage? ----- Original Message ----- From: Roxanna Nakamura <[log in to unmask]> To: <[log in to unmask]> Sent: Thursday, March 16, 2000 1:25 PM Subject: Levodopa toxicity a myth? > I just came across these interesting new articles in the > AMA's Archives of Neurology: > > "Is Levodopa toxic?" > http://archneur.ama-assn.org/issues/current/full/ncn8639.html > > "Levodopa toxicity in Parkinson Disease: Reality or Myth?" > http://archneur.ama-assn.org/issues/current/full/ncn8638.html > > "Levodopa toxicity" > http://archneur.ama-assn.org/issues/current/full/ncn8640.html > > Despite the titles, these articles are encouraging. > Apparently, research does *not* support the theory that > levodopa hastens disease progression or cell death. On the > contrary, levodopa extends life and decreases disability. > The real "toxicity" concern, the authors say, is whether/how > levodopa really is related to motor fluctuations and > dyskinesia.