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-----Oorspronkelijk bericht----- Van: Carol Ann Schepperley <[log in to unmask]> Aan: [log in to unmask] <[log in to unmask]> Datum: vrijdag 24 maart 2000 3:25 Onderwerp: Re: Pergolide without Levodopa >> What exactly does pergolide do? And how does it help without senemet? << Pergolide contains an artificial compound that functionally is comparable with dopamine. Pergolide CAN cross the blood-brain-barrier, and act directly upon the dopamine receptors in the brain. Hans.