Frans van Duinen wrote: > Does anyone know a good (any) resource on the effect of specific medications > on the vitamins and other nutrients in the body? > The reason I'm asking is that for the last two weeks I've had this > excruciating lower back pain (pinched nerve?), as well as the occasional leg > muscle cramp. (commonly signs of lack of calcium) > This coincides with a new regime of Permax (still ramping up) and 3x2 > Domperidone (anti nausea). Frans -- In regard to Permax, the following is excerpted from an adverse reactions report on pergolide (Permax): "For the body as a whole, pain has been reported at a variety of sites while taking pergolide. These include chest, neck and back pain." As you state the pain coincides with your use of Permax, I think it would be a good idea to discuss this with your physician. My very best regards, Kathrynne -- Kathrynne Holden, MS, RD Author: "Eat well, stay well with Parkinson's disease" "Constipation and Parkinson's" -- audiocassette & guidebook "Guidelines for Medical Nutrition Therapy for Parkinson's disease" & Risk Assessment Tools "Risk for malnutrition and bone fracture in Parkinson's disease," J Nutr Elderly. V18:3;1999. http://www.nutritionucanlivewith.com/