THANKS Hans!!!
What great news.
This will be useful information for determining the cause of PD.
If this is a neuro-preservative, it will be a big relief to many.
Did you do the translation?
What publication is this article in?
Hans van der Genugten wrote:
> Date: 22-03-2000
> Translation: HvdG
> Source: University Medical Center St. Radboud, Nijmegen, The
> Netherlands.
>
> THC 346 stops symptoms of PD in monkeys
>
> Two neurobiologists from Nijmegen (the Netherlands) have found the compound
> THC 346 to stop the progression of PD in monkeys completely. Within 3 months
> a trial will start with PWP. The medicine might also have a positive effect
> upon ALS and Alzheimers.
>
> One of the researchers, Prof. dr. A. Cools of the University Medical Center
> St. Radboud, said the discovery to be every researchers dream. He and his
> collegue Andringa could not believe it when they saw the effect of THC 346
> in tests with rhesus monkeys. Worldwide researchers never before succeeded
> in actually stopping the progression of PD, Cools said.
>
> THC346 stops the apoptose of the neurons completely. This was found in
> studies with rats and rhesus monkeys, injected with a compound that induced
> PD. The sick monkeys that then had an injection of THC 346, showed no more
> progression in motoric or behavioral problems. Cools is convinced that these
> effects will also be found in the study with humans. THC 346 can be taken
> orally (pill) by PWP.
>
> The neurobiologist stressed that the compound does not cure PD. Symptoms
> that already appeared, will stay. But if PWP have their first symptoms,
> these symptoms are still minimal. Untill now therapy was often delayed
> because of severe side-effects of the available medication. THC346 makes it
> possible to stop the progression in an early phase at a level that people
> still can function quite normal.
>
> The researchers are still trying to find out how much and how long THC 346
> has to be taken to stop the apoptosis of the neurons definitively. Cools
> hopes one period of treatment will be sufficient in the early phase of PD.
> In advanced PD it will probably take several treatment periods to stop the
> progression.
>
> THC 346 is tested upon healthy persons in Switzerland and found to be save.
> Cools expects worldwide studies of THC 346 use for ALS and Huntington's to
> start within the year. These diseases are also due to apoptosis. If the
> human trials with PWP have the same effects as the studies with monkeys, the
> medication is expected to be available to the public in 3-5 years.
--
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Ray Strand
mailto:[log in to unmask]
48/47/45?
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...on the edge of the prairie abyss ......................
