Dear Fred, My prayers are with you and Barb, I will be thinking of her daily. With regard to rhabdomyolosis, it is listed as a possible adverse reaction under pramipexole. Also, please ask her physicians to consider use of Elavil as a possible contributing factor, at least to the dyskinesias. Although it is generally considered to be safe, a client of mine (much older than Barb) was using it and had adverse consequences. Under "Contraindications" for amitryptiline (Elavil) is stated: 'Parkinson's disease' -- Tricyclic antidepressants should be used with caution in patients with Parkinson's disease. Tricyclic antidepressants rarely can induce or worsen extrapyramidal symptoms. In addition, involuntary movements, which appear to be tardive dyskinesia, can occur. ' I am praying for Barb, please keep us updated on her progress. My very best to you both, Kathrynne -- Kathrynne Holden, MS, RD Author: "Eat well, stay well with Parkinson's disease" "Constipation and Parkinson's" -- audiocassette & guidebook "Guidelines for Medical Nutrition Therapy for Parkinson's disease" & Risk Assessment Tools "Risk for malnutrition and bone fracture in Parkinson's disease," J Nutr Elderly. V18:3;1999. http://www.nutritionucanlivewith.com/