Audrey C, my husband has had dexterity problems for quite some time. This problem started several yrs before his PD diagnosis. Looking back we truly believe this was one of his earliest symptoms.Even though his tremors and balance seem to be somewhat controlled with his senemet his hand dexterity is very limited. He has problems holding onto things and even at times being able to control any type of firm grip. Hope this gives you just a little idea that there are others that do have this problem. Juanita CG for George 73 dx 2 + yrs