Dear Fred, I believe it is very important to get the exact names of all medications Barbara is taking. Is it possible she is taking Percodan? Here are some possible adverse reactions: Ativan (lorazepam) Patients receiving levodopa for Parkinson's disease can experience decreased control of the symptoms of this disease when benzodiazepines are added to their regimen. Benzodiazepines should be administered cautiously to such patients. Concomitant administration of lorazepam with CNS-depressant drugs, including opiate agonists, phenothiazines, barbiturates, ethanol, HÀ-blockers, general anesthetics, and tricyclic antidepressants, can potentiate the CNS effects (i.e., increased sedation or respiratory depression) of either agent. Parlodel (bromocriptine) http://www.ionet.net/~jcott/homepage/drugdb/020.html (Bromocriptine and levodopa are both dopamine agonists. Concomitant use of these agents can cause additive neurologic effects. Although this drug combination may be necessary in some patients, dosages of levodopa may require reduction if bromocriptine is added. ) Percocet http://www.ionet.net/~jcott/homepage/drugdb/096.html (dopamine antagonist -- high risk) Please give Barbara my very best wishes for a speedy recovery; she is in my thoughts and prayers. Best, Kathrynne -- Kathrynne Holden, MS, RD Author: "Eat well, stay well with Parkinson's disease" "Constipation and Parkinson's" -- audiocassette & guidebook "Guidelines for Medical Nutrition Therapy for Parkinson's disease" & Risk Assessment Tools "Risk for malnutrition and bone fracture in Parkinson's disease," J Nutr Elderly. V18:3;1999. http://www.nutritionucanlivewith.com/