Hi! I don't mean to be a pest. I'm thinking my message yesterday was so wordy, it was hard for people to identify what I was asking. So, here are my questions again, but this time they are not as convoluted (I hope): Does anyone have experience, knowledge or hints about what drugs might ease my mother's muscle cramps, rigidity, and more intense tremors -- which now occur about 90 minutes before and 90 minutes after each Sinemet CR dose? She weighs 155 lbs. She is 80/15. Her drug schedule now is Sinemet 50/200: 8 am, 2 pm, 8 pm. Tylenol 1000 mg 3 x day. Dilantin 100 mg 2 x day. Multivitamin The intensification of cramps, rigidity, and tremors began when she was tapered off of Zyprexa, an anti-psychotic, which I've learned also has some anticholinergic action. Many thanks! -- Lynne