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I've thought about the irony of quitting smoking 15 years ago, then running marathons and triathlons, only to be diagnosed with PK a year ago at 58 after symptoms developed for several years. The irony is all my ancestors on my maternal side have used tobacco into their 80s and are still going strong. I read the same nicotine material at NPF site and another PK website. I know one PK who claimed improvement in symptoms while using nicotine (via snuff or whatever its called) after being nicotine free for many years. I'd sure like to hear from anyone with first hand experience with patches or other non-smoking delivery system (gum, whatever). My doc acknowledges the research but still thinks the negatives outweight the positives. With an 86 year old uncle using those little tobacco pouches (he quit smoking at about 78) and in good health for his age, I have mixed feelings about avoiding nicotine, especially if it helps symptoms as well as being probably neuroprotective. Chuck