Chris van der Linden, M.D.wrote: > As a neurologist and movement disorder specialist, treating 100's of > Parkinson patients, I fully agree. Most patients who are send to me for DBS > treatment are not well pharmacologically controlled and in many patients I > can adjust (read: increase levodopa) the medication, so that the quality off > life improves and surgery is (not yet) necessary or warranted. > > Chris van der Linden, M.D. > St. Lucas Hospital Ghent > Belgium The above message was written in February. Sorry. I'm trying to catch up. When I tried Sinemet CR (25/100) three times a day, it worked against me instead of helping me. I tried this a year ago and again quite recently. My only obvious symptom is a severe (my word) tremor. When I took the Sinemet it caused my left side to lock up. I walked as if I had had a stroke, and I was slowed way down - dragging my left leg. I felt like I had less dopamine instead of more. The tremor was not visibly affected. Is it possible that increasing the dose would have given better results? Joan D.