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>I just took my first dose of sinemet and am having a bad reaction, I have >tremor as only symptom, took 1/2 of 25/100 witha light meal at 5pm, two >hours later my tremor in 4 times as violent as it has ever been, just talked >to doctor, he was no help, just said that sometimes sinemet does not help >tremor. what is going on here, i never heard of sinemet making sympoms worse >rather than better. > >Lanier Maddux 64,4 hi, Lanier, you may have gotten the sinemet into the bloodstream with enough protein that the delayed effect produced the maximum concentration of levodopa in your plasma about 2 hours after the pill was taken. assuming that to be the case, your 'tremor' may have been dyskinesia. it seems unlikely with only half a tablet. is your tremor one side only? both sides? just conjecturing, but i have been studying this for several years. ron -- Ron Vetter 1936, '84 PD dz mailto:[log in to unmask] http://www.ridgecrest.ca.us/~rfvetter