Dear Dr. Romero, Thank you very much for your concern. Today my neurologist requested that the pharmacy where my prescriptions are filled supply me with Sinemet 25/100 instead of generic carbidopa/levodopa 25/100. The pharmacist called me later this morning. She said that at 1:00 PM tomorrow, the new Rx for Sinemet 25/100 will be ready for me. I also want to thank the many list members who have been writing with suggestions for me. Ivan Suzman 50 yrs/39 diagnosis /36 onset of recognizable PD symptoms On Sat, 22 Apr 2000 16:10:42 -0500 "Jorge A. Romero, M.D." <[log in to unmask]> writes: > The problem is not that generics or brand name are superior. The > problem is > that they are not exactly equivalent to each other and some people > who > switch may find that they need to be "re-titrated" if you have > already been > stabilized on brand name. Just let your neurologist know and he may > have > some suggestions for readjustment. > > It is unfair that they force people to switch if they are stable on > one > medication, but that's the law - written by people who are not > medical and > don't understand the concepts of bio-equivalence well. > > In any event, generic levodopa works well if you stick to it. It > will work > as well as the brand name, and will be less expensive. However, > switching > back and forth will create problems, or even switching between two > different > generics, if in the future someone else comes out with a third > generic > alternative. Make sure you insist that your pharmacy dispense THE > SAME > generic each time. > > > Jorge Romero, MD