Hi All, Kathrynne Holden used my name in reference to a past post on NMS... Date: Sat, 7 Aug 1999 08:08:19 -0700 Hi Friends, Here are some URL's for those interested in learning more about NMS. I "stole" the following paragraph from the first site listed, 'cuz it says precisely what I wanted to say to preface these URL's..... All medicines have side effects. But most medicines have more benefits than side effects and the side effects can be controlled. But the problem is doctors are often less than honest about the side effects and consumers are uninformed about them. So when the individual develops side effects they don't what to do or get scared away from the medicine. On the other hand, if they were fully informed beforehand, they would know just what to do when the effects come. Following are articles on Neuroleptic Malignant Syndrome.... http://www.nami-nyc-metro.org/meds/sidefx.html http://www.vh.org/Providers/Conferences/CPS/09.html Knowledge can't hurt............. Happy surfin' ............ murray >>> Posting number 65470, dated 7 Aug 1999 09:06:41 Hi Friends, Here is a little more on NMS..... Title Neuroleptic malignant syndrome. Recognition, prevention and management. Author Velamoor VR Address London Health Science Centre, Ontario, Canada. Source Drug Saf, 19(1):73-82 1998 Jul Abstract Neuroleptic malignant syndrome (NMS) is a rare but potentially lethal form of drug-induced hyperthermia characterised by mental status changes, muscle rigidity, hyperthermia and autonomic dysfunction. Increased awareness and early recognition will lead to prompt management. The diagnosis of NMS presents a challenge because several medical conditions generate similar symptoms. The presentation and course of NMS can be quite variable ranging from a stormy and potentially fatal course to a relatively benign and self-limiting course. The most important aspect of treatment is prevention. This includes reducing risk factors (e.g. dehydration, agitation and exhaustion), early recognition of suspected cases and prompt discontinuation of the offending agent. All patients with psychosis should be monitored daily for dehydration and elevated temperature, have vital signs checked and agitation should be watched for. Antipsychotics should be used conservatively with gradual titration of doses. The management of NMS should be based on a hierarchy of symptom severity. Following an episode of NMS, the patient should be reassessed for further treatment with antipsychotics and rechallenge should not be attempted at least 2 weeks following resolution of symptoms of NMS. The patient and family should be educated about the episode and consent for further medication use obtained after a clear explanation of the risk-benefit analysis. amen.........murray Hi Again, Here are today's search results on NMS... Neuroleptic Malignant Syndrome http://www.nmsis.org/ NMS Hotline http://www.nmsis.org/hotline.htm DSM IV http://www.behavenet.com/capsules/disorders/medindmovdis.htm NEUROLOGIC MALIGNANT SYNDROME (NMS) 1959-1980 A CHRONOLOGICAL ANNOTATED BIBLIOGRAPHY prepared by John M. Friedberg, MD February 5, 1997 http://www.idiom.com/~drjohn/biblio.html NEUROLEPTIC MALIGNANT SYNDROME mini information sheet http://www.ninds.nih.gov/patients/Disorder/neuroleptic-malignant/neuroleptic-malignant.htm The International Coalition for Drug Awareness What is Serotonin Syndrome? http://www.drugawareness.org/serosyndrome.html Drug Toxicity http://www.ohsu.edu/cliniweb/C21/C21.613.276.html Regards .............. murray [log in to unmask]