While Peter has never been "clinically depressed" he did experience dep[ression for a number of years prior to being dxd with PD. Other early symptoms were memory problems and constipation. No reason for these was discovered until 1989 when he dxd himself woth PD, which the doc promptly confirmed.Significant then was stiffness of arms (lack of swing) cogwheeling of arm, vry minor tremor of right thumb--he still has little tremor. I tend to suspect that the early depression was a PD-is-coming symptom but we had no idea at the time. For the past several years he has taken Prozac, and while it doesn't make him "Bozo the Clown" it does lighten his mood. I tend to believe it was only partly "situational", as he didn't know he had PD, and was more a personality trait, never severe enough for hospitalization, etc. FWIW--- Camilla Flintermann, CG for Peter 82/70/55 Oxford, Ohio http://www.newcountry.nu/pd/members/camilla/one.htm <[log in to unmask]> also, on PDWebring at http://members.tripod.lycos.nl/genugten/flinterm.htm "Ask me about the CARE list for Caregivers of Parkinsonians ! " And visit the CARE webring at http://www.crosswinds.net/~caregivers/index.html