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hi all this discussion on clinical depression has triggered something else i have been mulling about for awhile is pd unique in terms of its "on-off" phenomenon as compared with other 'disabilities'? is there any other 'chronic degenerative condition' which can change from a virtually 'cured' appearance symptomatically to severe incapacity several times in a day as part of its 'normal' manifestation? [speaking for myself of course and any other parkie who may be at an on-off plateau like mine] if this is unique to pd i wonder what kind of impact this 'cycling' has on us psychologically? if any? [pun not intended, honest] do we go through a range of emotions [maybe subconsciously] from "it's a miracle!! i'm cured!!" to "ono, i'm paralysed again" and if we do that several times per day are we exposed to extreme stress without necessarily being conscious of it? just musing and mulling... janet who thinks she has 'accepted' her pd fairly well... janet paterson 53 now / 41 dx / 37 onset 613 256 8340 / PO Box 171 Almonte Ontario K0A 1A0 Canada come visit my website "a new voice" at: http://www.geocities.com/janet313/