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Dear Fran, My answer may not count because I've had DBS STN surgery and have had Parkinson's for 21 years but when the battery died last year I had to go back on medication while I waited for a new one. I chose Symmetryl with the Mirapex that I still take. Symmetryl was the most effective drug that I took over the many years, but it didn't work this time. I don't know if it was because it was generic, or a result of the surgery. Since the surgery 4 years ago, I haven't taken Sinemet. > Is anyone who has been diagnosed a year ago taking Amantadine in combination > with Mirapex? Any information on how you are doing with the Mirapex will be > appreciated. I am not taking any Sinemet as yet. > > Thank you. > > Fran Landes > 46/45/43