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Dennis, my MDS has recently discussed with me my complaint of fatigue which has plagued me for months. She maintains that this is related to depression, and I insist I am not depressed. My life is busy and full of activities which I enjoy and friends with whom I share much. But this fatigue has got to go, and I'm stuck with it. Yes, I feel sad at times, and have many aches and pains, but mostly I go ahead with my life. My doc didn't suggest an antidepressant nor did I request one. What do others do for this fatigue....it's debilitating! Clare Wilson (69/ 3 )