Hi all... Recently during a hospital stay, two of my PD meds were changed: A. My agoniist -- Miirapex to Parlodel (Bromocriptine) B. My COMT -- from Tasmar to Comtan (Entacapone) 200 mg/dose I would like to know: 1. My understanding is that Comtan needs to be taken with each dose of Sinemet in order to boost the effectiveness of the Sinemet. Is there a window of time after takiing the Sinemet in which one may still benefit from taking the Comtan? 2. I take this pill generally in fruit jelly. It seems 'chalky' to me and I often find I have a reflux reaction or upset stomach (no matter what substance I use with it).. Is this very common with this med? thanks Barbara Blake-Krebs 59/44 [log in to unmask]